The Inflammatory Transcription Factors NFKB, STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human Kidney: e1005734

Human kidney function declines with age, accompanied by stereotyped changes in gene expression and histopathology, but the mechanisms underlying these changes are largely unknown. To identify potential regulators of kidney aging, we compared age-associated transcriptional changes in the human kidney...

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Veröffentlicht in:	PLoS genetics 2015-12, Vol.11 (12)
Hauptverfasser:	O'Brown, Zach K, Nostrand, Eric LVan, Higgins, John P, Kim, Stuart K
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aging Datasets Experiments Gene expression Genomes Genomics Histopathology Inflammation Kidney diseases Older people Senescence Transcription factors
Online-Zugang:	Volltext
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