Renin-angiotensin-aldosterone-system inhibition is safe in the preoperative period surrounding carotid endarterectomy

Objective Discontinuation of angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) medications before surgery has been suggested because of the potentially deleterious effects of hypotension. We investigated the effect of preoperative ACEI and/or ARB use on early outc...

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Veröffentlicht in:	Journal of vascular surgery 2016-03, Vol.63 (3), p.715-721
Hauptverfasser:	Steely, Andrea M., MD, Callas, Peter W., PhD, Bertges, Daniel J., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Angiotensin II Type 1 Receptor Blockers - administration & dosage Angiotensin II Type 1 Receptor Blockers - adverse effects Angiotensin-Converting Enzyme Inhibitors - administration & dosage Angiotensin-Converting Enzyme Inhibitors - adverse effects Carotid Artery Diseases - complications Carotid Artery Diseases - diagnosis Carotid Artery Diseases - mortality Carotid Artery Diseases - surgery Chi-Square Distribution Databases, Factual Drug Administration Schedule Endarterectomy, Carotid - adverse effects Endarterectomy, Carotid - mortality Female Humans Hypertension - complications Hypertension - diagnosis Hypertension - drug therapy Hypertension - mortality Hypertension - physiopathology Logistic Models Male Middle Aged Multivariate Analysis New England Odds Ratio Perioperative Care Postoperative Complications - etiology Postoperative Complications - mortality Propensity Score Renin-Angiotensin System - drug effects Retrospective Studies Risk Assessment Risk Factors Surgery Time Factors Treatment Outcome
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