Protein-quantum dot nanohybrids for bioanalytical applications
Quantum dots (QDs) coupled with biomolecules play an important role as optically and chemically stable bioimaging agents for various applications. These inorganic–biological hybrid conjugates have been demonstrated as powerful fluorescence tools for sensing, diagnostics, and labeling. This review fo...
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Veröffentlicht in: | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2016-03, Vol.8 (2), p.178-190 |
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description | Quantum dots (QDs) coupled with biomolecules play an important role as optically and chemically stable bioimaging agents for various applications. These inorganic–biological hybrid conjugates have been demonstrated as powerful fluorescence tools for sensing, diagnostics, and labeling. This review focuses on protein–QD nanohybrids for different types of bioanalytical applications. There are various strategies to modify the surface properties of QDs to produce protein–QD nanohybrids that are stable in biological fluids. We expect that multifunctional protein–QD nanohybrids can be used as a powerful optical probe for various biological applications. WIREs Nanomed Nanobiotechnol 2016, 8:178–190. doi: 10.1002/wnan.1345
This article is categorized under:
Diagnostic Tools > Biosensing
Diagnostic Tools > Diagnostic Nanodevices
Diagnostic Tools > In Vitro Nanoparticle-Based Sensing |
doi_str_mv | 10.1002/wnan.1345 |
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This article is categorized under:
Diagnostic Tools > Biosensing
Diagnostic Tools > Diagnostic Nanodevices
Diagnostic Tools > In Vitro Nanoparticle-Based Sensing</description><identifier>ISSN: 1939-5116</identifier><identifier>EISSN: 1939-0041</identifier><identifier>DOI: 10.1002/wnan.1345</identifier><identifier>PMID: 25854126</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Animals ; Biomarkers - metabolism ; Biomolecules ; Biosensing Techniques - methods ; Biosensors ; Diagnostic software ; Diagnostic systems ; Fluorescence ; Humans ; Medical imaging ; Nanoparticles ; Nanoparticles - chemistry ; Nanotechnology devices ; Optical Phenomena ; Proteins ; Proteins - metabolism ; Quantum dots ; Quantum Dots - metabolism ; Surface properties</subject><ispartof>Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2016-03, Vol.8 (2), p.178-190</ispartof><rights>2015 Wiley Periodicals, Inc.</rights><rights>2016 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5265-3b29ab898197a00fc307a3de476c93ccc1fbd7212b9b21789dc9b690906831e43</citedby><cites>FETCH-LOGICAL-c5265-3b29ab898197a00fc307a3de476c93ccc1fbd7212b9b21789dc9b690906831e43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fwnan.1345$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fwnan.1345$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25854126$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Jeong Yu</creatorcontrib><creatorcontrib>Kim, Jee Seon</creatorcontrib><creatorcontrib>Park, Jae Chul</creatorcontrib><creatorcontrib>Nam, Yoon Sung</creatorcontrib><title>Protein-quantum dot nanohybrids for bioanalytical applications</title><title>Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology</title><addtitle>WIREs Nanomed Nanobiotechnol</addtitle><description>Quantum dots (QDs) coupled with biomolecules play an important role as optically and chemically stable bioimaging agents for various applications. These inorganic–biological hybrid conjugates have been demonstrated as powerful fluorescence tools for sensing, diagnostics, and labeling. This review focuses on protein–QD nanohybrids for different types of bioanalytical applications. There are various strategies to modify the surface properties of QDs to produce protein–QD nanohybrids that are stable in biological fluids. We expect that multifunctional protein–QD nanohybrids can be used as a powerful optical probe for various biological applications. WIREs Nanomed Nanobiotechnol 2016, 8:178–190. doi: 10.1002/wnan.1345
This article is categorized under:
Diagnostic Tools > Biosensing
Diagnostic Tools > Diagnostic Nanodevices
Diagnostic Tools > In Vitro Nanoparticle-Based Sensing</description><subject>Animals</subject><subject>Biomarkers - metabolism</subject><subject>Biomolecules</subject><subject>Biosensing Techniques - methods</subject><subject>Biosensors</subject><subject>Diagnostic software</subject><subject>Diagnostic systems</subject><subject>Fluorescence</subject><subject>Humans</subject><subject>Medical imaging</subject><subject>Nanoparticles</subject><subject>Nanoparticles - chemistry</subject><subject>Nanotechnology devices</subject><subject>Optical Phenomena</subject><subject>Proteins</subject><subject>Proteins - metabolism</subject><subject>Quantum dots</subject><subject>Quantum Dots - metabolism</subject><subject>Surface properties</subject><issn>1939-5116</issn><issn>1939-0041</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKxDAUQIMoPkYX_oAU3OiimneajSCiozKMLhTBTUjSFKOdZkxadP7elhldCLrKXZx7bjgA7CN4giDEpx-Nbk4QoWwNbCNJZA4hReurmSHEt8BOSq8Qcsox2wRbmBWMIsy3wdl9DK3zTf7e6abtZlkZ2qzXhZeFib5MWRViZnzQja4Xrbe6zvR8XvdD60OTdsFGpevk9lbvCDxeXT5cXOeTu_HNxfkktwxzlhODpTaFLJAUGsLKEig0KR0V3EpirUWVKQVG2EiDkShkaaXhEkrIC4IcJSNwtPTOY3jvXGrVzCfr6lo3LnRJIcELxjimrEcPf6GvoYv995PCEApJGcXkP2pw9c0wHc4eLykbQ0rRVWoe_UzHhUJQDenVkF4N6Xv2YGXszMyVP-R36x44XQIfvnaLv03qaXo-XSnz5YZPrfv82dDxTXFBxECO1cNkenvF5LO6J1_AHps7</recordid><startdate>201603</startdate><enddate>201603</enddate><creator>Lee, Jeong Yu</creator><creator>Kim, Jee Seon</creator><creator>Park, Jae Chul</creator><creator>Nam, Yoon Sung</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>7QP</scope><scope>7TK</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>201603</creationdate><title>Protein-quantum dot nanohybrids for bioanalytical applications</title><author>Lee, Jeong Yu ; Kim, Jee Seon ; Park, Jae Chul ; Nam, Yoon Sung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5265-3b29ab898197a00fc307a3de476c93ccc1fbd7212b9b21789dc9b690906831e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Animals</topic><topic>Biomarkers - metabolism</topic><topic>Biomolecules</topic><topic>Biosensing Techniques - methods</topic><topic>Biosensors</topic><topic>Diagnostic software</topic><topic>Diagnostic systems</topic><topic>Fluorescence</topic><topic>Humans</topic><topic>Medical imaging</topic><topic>Nanoparticles</topic><topic>Nanoparticles - chemistry</topic><topic>Nanotechnology devices</topic><topic>Optical Phenomena</topic><topic>Proteins</topic><topic>Proteins - metabolism</topic><topic>Quantum dots</topic><topic>Quantum Dots - metabolism</topic><topic>Surface properties</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Jeong Yu</creatorcontrib><creatorcontrib>Kim, Jee Seon</creatorcontrib><creatorcontrib>Park, Jae Chul</creatorcontrib><creatorcontrib>Nam, Yoon Sung</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Jeong Yu</au><au>Kim, Jee Seon</au><au>Park, Jae Chul</au><au>Nam, Yoon Sung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Protein-quantum dot nanohybrids for bioanalytical applications</atitle><jtitle>Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology</jtitle><addtitle>WIREs Nanomed Nanobiotechnol</addtitle><date>2016-03</date><risdate>2016</risdate><volume>8</volume><issue>2</issue><spage>178</spage><epage>190</epage><pages>178-190</pages><issn>1939-5116</issn><eissn>1939-0041</eissn><abstract>Quantum dots (QDs) coupled with biomolecules play an important role as optically and chemically stable bioimaging agents for various applications. These inorganic–biological hybrid conjugates have been demonstrated as powerful fluorescence tools for sensing, diagnostics, and labeling. This review focuses on protein–QD nanohybrids for different types of bioanalytical applications. There are various strategies to modify the surface properties of QDs to produce protein–QD nanohybrids that are stable in biological fluids. We expect that multifunctional protein–QD nanohybrids can be used as a powerful optical probe for various biological applications. WIREs Nanomed Nanobiotechnol 2016, 8:178–190. doi: 10.1002/wnan.1345
This article is categorized under:
Diagnostic Tools > Biosensing
Diagnostic Tools > Diagnostic Nanodevices
Diagnostic Tools > In Vitro Nanoparticle-Based Sensing</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>25854126</pmid><doi>10.1002/wnan.1345</doi><tpages>13</tpages></addata></record> |
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subjects | Animals Biomarkers - metabolism Biomolecules Biosensing Techniques - methods Biosensors Diagnostic software Diagnostic systems Fluorescence Humans Medical imaging Nanoparticles Nanoparticles - chemistry Nanotechnology devices Optical Phenomena Proteins Proteins - metabolism Quantum dots Quantum Dots - metabolism Surface properties |
title | Protein-quantum dot nanohybrids for bioanalytical applications |
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