Protein-quantum dot nanohybrids for bioanalytical applications

Quantum dots (QDs) coupled with biomolecules play an important role as optically and chemically stable bioimaging agents for various applications. These inorganic–biological hybrid conjugates have been demonstrated as powerful fluorescence tools for sensing, diagnostics, and labeling. This review fo...

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Veröffentlicht in:Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2016-03, Vol.8 (2), p.178-190
Hauptverfasser: Lee, Jeong Yu, Kim, Jee Seon, Park, Jae Chul, Nam, Yoon Sung
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Nam, Yoon Sung
description Quantum dots (QDs) coupled with biomolecules play an important role as optically and chemically stable bioimaging agents for various applications. These inorganic–biological hybrid conjugates have been demonstrated as powerful fluorescence tools for sensing, diagnostics, and labeling. This review focuses on protein–QD nanohybrids for different types of bioanalytical applications. There are various strategies to modify the surface properties of QDs to produce protein–QD nanohybrids that are stable in biological fluids. We expect that multifunctional protein–QD nanohybrids can be used as a powerful optical probe for various biological applications. WIREs Nanomed Nanobiotechnol 2016, 8:178–190. doi: 10.1002/wnan.1345 This article is categorized under: Diagnostic Tools > Biosensing Diagnostic Tools > Diagnostic Nanodevices Diagnostic Tools > In Vitro Nanoparticle-Based Sensing
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subjects Animals
Biomarkers - metabolism
Biomolecules
Biosensing Techniques - methods
Biosensors
Diagnostic software
Diagnostic systems
Fluorescence
Humans
Medical imaging
Nanoparticles
Nanoparticles - chemistry
Nanotechnology devices
Optical Phenomena
Proteins
Proteins - metabolism
Quantum dots
Quantum Dots - metabolism
Surface properties
title Protein-quantum dot nanohybrids for bioanalytical applications
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