The strange case of the [13N]NH3: validation of the production process for human use

OBJECTIVEPET radiopharmaceuticals are often injected in patients before all quality controls are performed and before sterility results are available. We propose a process validation to produce very safe and pure [N]NH3 for human use. METHODS[N]NH3 was produced in the cyclotron target. Online purifi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nuclear medicine communications 2016-04, Vol.37 (4), p.412-421
Hauptverfasser:	Statuto, Massimo, Galli, Elisa, Bertagna, Francesco, Migliorati, Elena, Zanella, Isabella, Di Lorenzo, Diego, De Agostini, Antonio, Rodella, Carlo, Apostoli, Pietro, Caimi, Luigi, Giubbini, Raffaele, Biasiotto, Giorgio
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonia - chemistry Humans Hydrogen-Ion Concentration Nitrogen Radioisotopes Osmolar Concentration Quality Control Radiochemistry - methods Radiopharmaceuticals - chemistry Solvents - chemistry Sterilization
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!