Effects of ramp-up of inspired airflow on in vitro aerosol dose delivery performance for certain dry powder inhalers

This study investigated the effect of airflow ramp-up on the dose delivery performance of seven dry powder inhalers, covering a broad range of powder formulations and powder dispersion mechanisms. In vitro performance tests were performed at a target pressure drop of 4kPa, using two inspiratory flow...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2016-03, Vol.84, p.46-54
Hauptverfasser:	Ung, Keith T., Chan, Hak-Kim
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosol emission kinetics Aerosols - administration & dosage Aerosols - pharmacokinetics Alberta idealized throat Dose delivery performance Dry powder inhaler Dry Powder Inhalers Flow ramp Humans Inspiratory flow-rate Lung - metabolism
Online-Zugang:	Volltext
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