Heated humidified high flow nasal cannula versus nasal continuous positive airway pressure as primary mode of respiratory support for respiratory distress in preterm infants
Objective To compare the outcomes of preterm infants with respiratory distress initiated on either Heated Humidified High Flow Nasal Cannula or Nasal Continuous Positive Airway Pressure as a primary mode of respiratory support. Study Design Prospective observational cohort study Setting Tertiary car...
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Veröffentlicht in: | Indian pediatrics 2016-02, Vol.53 (2), p.129-133 |
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creator | Hegde, Deeparaj Mondkar, Jayashree Panchal, Harshad Manerkar, Swati Jasani, Bonny Kabra, Nandkishor |
description | Objective
To compare the outcomes of preterm infants with respiratory distress initiated on either Heated Humidified High Flow Nasal Cannula or Nasal Continuous Positive Airway Pressure as a primary mode of respiratory support.
Study Design
Prospective observational cohort study
Setting
Tertiary care level III neonatal intensive care unit
Participants
88 preterm infants between 28 to 34 weeks of gestation with mild to moderate respiratory distress within 6 hours of birth.
Intervention
Eligible infants were treated either with Heated Humidified High Flow Nasal Cannula (
n
=46) or Nasal Continuous Positive Airway Pressure (
n
=42).
Primary outcome
Need for mechanical ventilation within 72 hrs of initiating support.
Results
Baseline demographic characteristics were comparable between the two groups. There was no difference in the requirement of mechanical ventilation between Heated Humidified High Flow Nasal Cannula (19.5%) and Nasal Continuous Positive Airway Pressure (26.2%) groups [RD–0.74 (95% CI 0.34–1.62;
P
=0.46)]. Moderate or severe nasal trauma occurred less frequently with Heated Humidified High Flow Nasal Cannula (10.9%) in comparison to Nasal Continuous Positive Airway Pressure (40.5%) (
P
= 0.004).
Conclusion
Heated Humidified High Flow Nasal Cannula was comparable to Nasal Continuous Positive Airway Pressure as a primary respiratory support for preterm infants with respiratory distress, with lesser incidence of nasal trauma. |
doi_str_mv | 10.1007/s13312-016-0806-3 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1767628405</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1767628405</sourcerecordid><originalsourceid>FETCH-LOGICAL-c344t-f719c94f5685468fc6e2ae6773a8a7075c4aa5f4f5fb27632d9f924fdf432b943</originalsourceid><addsrcrecordid>eNp9Uctu3SAURFWq5tF-QDcVy2zc8jKYZRU1SaVI2bRrxLUhIbLB5UCifFT-sVj3plI3WTHMzBlpNAh9puQrJUR9A8o5ZR2hsiMDkR1_h06IVqJTfa-PGiZUd5JIeoxOAR4IYZz19AM6ZnLQigpxgl6unS1uwvd1CVPwYYPh7h77OT3haMHOeLQx1tniR5ehwiuZYgmxpkasCUIJjw7bkJ_sM16zA6i5_ZuWw2LzM17S5HDyuElryLakxkFd15QL9in_x08ByhaBQ9yyistLg97GAh_Re29ncJ8O7xn6ffnj18V1d3N79fPi-003ciFK5xXVoxa-l0Mv5OBH6Zh1UiluB6uI6kdhbe-bwe-YkpxN2msm_OQFZzst-Bk63-euOf2pDopZAoxunm10rbKhSirJBkH6ZqV765gTQHbeHDobSsy2ktmvZNpKZlvJ8Hbz5RBfd4ub_l28ztIMbG-AJsU7l81Dqjm2ym-k_gWylaK-</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1767628405</pqid></control><display><type>article</type><title>Heated humidified high flow nasal cannula versus nasal continuous positive airway pressure as primary mode of respiratory support for respiratory distress in preterm infants</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Hegde, Deeparaj ; Mondkar, Jayashree ; Panchal, Harshad ; Manerkar, Swati ; Jasani, Bonny ; Kabra, Nandkishor</creator><creatorcontrib>Hegde, Deeparaj ; Mondkar, Jayashree ; Panchal, Harshad ; Manerkar, Swati ; Jasani, Bonny ; Kabra, Nandkishor</creatorcontrib><description>Objective
To compare the outcomes of preterm infants with respiratory distress initiated on either Heated Humidified High Flow Nasal Cannula or Nasal Continuous Positive Airway Pressure as a primary mode of respiratory support.
Study Design
Prospective observational cohort study
Setting
Tertiary care level III neonatal intensive care unit
Participants
88 preterm infants between 28 to 34 weeks of gestation with mild to moderate respiratory distress within 6 hours of birth.
Intervention
Eligible infants were treated either with Heated Humidified High Flow Nasal Cannula (
n
=46) or Nasal Continuous Positive Airway Pressure (
n
=42).
Primary outcome
Need for mechanical ventilation within 72 hrs of initiating support.
Results
Baseline demographic characteristics were comparable between the two groups. There was no difference in the requirement of mechanical ventilation between Heated Humidified High Flow Nasal Cannula (19.5%) and Nasal Continuous Positive Airway Pressure (26.2%) groups [RD–0.74 (95% CI 0.34–1.62;
P
=0.46)]. Moderate or severe nasal trauma occurred less frequently with Heated Humidified High Flow Nasal Cannula (10.9%) in comparison to Nasal Continuous Positive Airway Pressure (40.5%) (
P
= 0.004).
Conclusion
Heated Humidified High Flow Nasal Cannula was comparable to Nasal Continuous Positive Airway Pressure as a primary respiratory support for preterm infants with respiratory distress, with lesser incidence of nasal trauma.</description><identifier>ISSN: 0019-6061</identifier><identifier>EISSN: 0974-7559</identifier><identifier>DOI: 10.1007/s13312-016-0806-3</identifier><identifier>PMID: 26897144</identifier><language>eng</language><publisher>New Delhi: Springer India</publisher><subject>Female ; Humans ; Humidity ; Infant, Newborn ; Infant, Premature ; Male ; Maternal and Child Health ; Medicine ; Medicine & Public Health ; Nasal Cavity - injuries ; Pediatric Surgery ; Pediatrics ; Prospective Studies ; Research Paper ; Respiration, Artificial - adverse effects ; Respiration, Artificial - instrumentation ; Respiration, Artificial - methods ; Respiration, Artificial - statistics & numerical data ; Respiratory Distress Syndrome, Newborn - epidemiology ; Respiratory Distress Syndrome, Newborn - therapy</subject><ispartof>Indian pediatrics, 2016-02, Vol.53 (2), p.129-133</ispartof><rights>Indian Academy of Pediatrics 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c344t-f719c94f5685468fc6e2ae6773a8a7075c4aa5f4f5fb27632d9f924fdf432b943</citedby><cites>FETCH-LOGICAL-c344t-f719c94f5685468fc6e2ae6773a8a7075c4aa5f4f5fb27632d9f924fdf432b943</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s13312-016-0806-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s13312-016-0806-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51298</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26897144$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hegde, Deeparaj</creatorcontrib><creatorcontrib>Mondkar, Jayashree</creatorcontrib><creatorcontrib>Panchal, Harshad</creatorcontrib><creatorcontrib>Manerkar, Swati</creatorcontrib><creatorcontrib>Jasani, Bonny</creatorcontrib><creatorcontrib>Kabra, Nandkishor</creatorcontrib><title>Heated humidified high flow nasal cannula versus nasal continuous positive airway pressure as primary mode of respiratory support for respiratory distress in preterm infants</title><title>Indian pediatrics</title><addtitle>Indian Pediatr</addtitle><addtitle>Indian Pediatr</addtitle><description>Objective
To compare the outcomes of preterm infants with respiratory distress initiated on either Heated Humidified High Flow Nasal Cannula or Nasal Continuous Positive Airway Pressure as a primary mode of respiratory support.
Study Design
Prospective observational cohort study
Setting
Tertiary care level III neonatal intensive care unit
Participants
88 preterm infants between 28 to 34 weeks of gestation with mild to moderate respiratory distress within 6 hours of birth.
Intervention
Eligible infants were treated either with Heated Humidified High Flow Nasal Cannula (
n
=46) or Nasal Continuous Positive Airway Pressure (
n
=42).
Primary outcome
Need for mechanical ventilation within 72 hrs of initiating support.
Results
Baseline demographic characteristics were comparable between the two groups. There was no difference in the requirement of mechanical ventilation between Heated Humidified High Flow Nasal Cannula (19.5%) and Nasal Continuous Positive Airway Pressure (26.2%) groups [RD–0.74 (95% CI 0.34–1.62;
P
=0.46)]. Moderate or severe nasal trauma occurred less frequently with Heated Humidified High Flow Nasal Cannula (10.9%) in comparison to Nasal Continuous Positive Airway Pressure (40.5%) (
P
= 0.004).
Conclusion
Heated Humidified High Flow Nasal Cannula was comparable to Nasal Continuous Positive Airway Pressure as a primary respiratory support for preterm infants with respiratory distress, with lesser incidence of nasal trauma.</description><subject>Female</subject><subject>Humans</subject><subject>Humidity</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Male</subject><subject>Maternal and Child Health</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nasal Cavity - injuries</subject><subject>Pediatric Surgery</subject><subject>Pediatrics</subject><subject>Prospective Studies</subject><subject>Research Paper</subject><subject>Respiration, Artificial - adverse effects</subject><subject>Respiration, Artificial - instrumentation</subject><subject>Respiration, Artificial - methods</subject><subject>Respiration, Artificial - statistics & numerical data</subject><subject>Respiratory Distress Syndrome, Newborn - epidemiology</subject><subject>Respiratory Distress Syndrome, Newborn - therapy</subject><issn>0019-6061</issn><issn>0974-7559</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Uctu3SAURFWq5tF-QDcVy2zc8jKYZRU1SaVI2bRrxLUhIbLB5UCifFT-sVj3plI3WTHMzBlpNAh9puQrJUR9A8o5ZR2hsiMDkR1_h06IVqJTfa-PGiZUd5JIeoxOAR4IYZz19AM6ZnLQigpxgl6unS1uwvd1CVPwYYPh7h77OT3haMHOeLQx1tniR5ehwiuZYgmxpkasCUIJjw7bkJ_sM16zA6i5_ZuWw2LzM17S5HDyuElryLakxkFd15QL9in_x08ByhaBQ9yyistLg97GAh_Re29ncJ8O7xn6ffnj18V1d3N79fPi-003ciFK5xXVoxa-l0Mv5OBH6Zh1UiluB6uI6kdhbe-bwe-YkpxN2msm_OQFZzst-Bk63-euOf2pDopZAoxunm10rbKhSirJBkH6ZqV765gTQHbeHDobSsy2ktmvZNpKZlvJ8Hbz5RBfd4ub_l28ztIMbG-AJsU7l81Dqjm2ym-k_gWylaK-</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Hegde, Deeparaj</creator><creator>Mondkar, Jayashree</creator><creator>Panchal, Harshad</creator><creator>Manerkar, Swati</creator><creator>Jasani, Bonny</creator><creator>Kabra, Nandkishor</creator><general>Springer India</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160201</creationdate><title>Heated humidified high flow nasal cannula versus nasal continuous positive airway pressure as primary mode of respiratory support for respiratory distress in preterm infants</title><author>Hegde, Deeparaj ; Mondkar, Jayashree ; Panchal, Harshad ; Manerkar, Swati ; Jasani, Bonny ; Kabra, Nandkishor</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c344t-f719c94f5685468fc6e2ae6773a8a7075c4aa5f4f5fb27632d9f924fdf432b943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Female</topic><topic>Humans</topic><topic>Humidity</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Male</topic><topic>Maternal and Child Health</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nasal Cavity - injuries</topic><topic>Pediatric Surgery</topic><topic>Pediatrics</topic><topic>Prospective Studies</topic><topic>Research Paper</topic><topic>Respiration, Artificial - adverse effects</topic><topic>Respiration, Artificial - instrumentation</topic><topic>Respiration, Artificial - methods</topic><topic>Respiration, Artificial - statistics & numerical data</topic><topic>Respiratory Distress Syndrome, Newborn - epidemiology</topic><topic>Respiratory Distress Syndrome, Newborn - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hegde, Deeparaj</creatorcontrib><creatorcontrib>Mondkar, Jayashree</creatorcontrib><creatorcontrib>Panchal, Harshad</creatorcontrib><creatorcontrib>Manerkar, Swati</creatorcontrib><creatorcontrib>Jasani, Bonny</creatorcontrib><creatorcontrib>Kabra, Nandkishor</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Indian pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hegde, Deeparaj</au><au>Mondkar, Jayashree</au><au>Panchal, Harshad</au><au>Manerkar, Swati</au><au>Jasani, Bonny</au><au>Kabra, Nandkishor</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heated humidified high flow nasal cannula versus nasal continuous positive airway pressure as primary mode of respiratory support for respiratory distress in preterm infants</atitle><jtitle>Indian pediatrics</jtitle><stitle>Indian Pediatr</stitle><addtitle>Indian Pediatr</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>53</volume><issue>2</issue><spage>129</spage><epage>133</epage><pages>129-133</pages><issn>0019-6061</issn><eissn>0974-7559</eissn><abstract>Objective
To compare the outcomes of preterm infants with respiratory distress initiated on either Heated Humidified High Flow Nasal Cannula or Nasal Continuous Positive Airway Pressure as a primary mode of respiratory support.
Study Design
Prospective observational cohort study
Setting
Tertiary care level III neonatal intensive care unit
Participants
88 preterm infants between 28 to 34 weeks of gestation with mild to moderate respiratory distress within 6 hours of birth.
Intervention
Eligible infants were treated either with Heated Humidified High Flow Nasal Cannula (
n
=46) or Nasal Continuous Positive Airway Pressure (
n
=42).
Primary outcome
Need for mechanical ventilation within 72 hrs of initiating support.
Results
Baseline demographic characteristics were comparable between the two groups. There was no difference in the requirement of mechanical ventilation between Heated Humidified High Flow Nasal Cannula (19.5%) and Nasal Continuous Positive Airway Pressure (26.2%) groups [RD–0.74 (95% CI 0.34–1.62;
P
=0.46)]. Moderate or severe nasal trauma occurred less frequently with Heated Humidified High Flow Nasal Cannula (10.9%) in comparison to Nasal Continuous Positive Airway Pressure (40.5%) (
P
= 0.004).
Conclusion
Heated Humidified High Flow Nasal Cannula was comparable to Nasal Continuous Positive Airway Pressure as a primary respiratory support for preterm infants with respiratory distress, with lesser incidence of nasal trauma.</abstract><cop>New Delhi</cop><pub>Springer India</pub><pmid>26897144</pmid><doi>10.1007/s13312-016-0806-3</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Springer Nature - Complete Springer Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Female Humans Humidity Infant, Newborn Infant, Premature Male Maternal and Child Health Medicine Medicine & Public Health Nasal Cavity - injuries Pediatric Surgery Pediatrics Prospective Studies Research Paper Respiration, Artificial - adverse effects Respiration, Artificial - instrumentation Respiration, Artificial - methods Respiration, Artificial - statistics & numerical data Respiratory Distress Syndrome, Newborn - epidemiology Respiratory Distress Syndrome, Newborn - therapy |
title | Heated humidified high flow nasal cannula versus nasal continuous positive airway pressure as primary mode of respiratory support for respiratory distress in preterm infants |
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