Paeoniflorin inhibits proliferation and invasion of breast cancer cells through suppressing Notch-1 signaling pathway

Abstract Paeoniflorin (PF), one of the major active ingredients of Chinese peony, was reported to possess anti-tumor effect. However, the role of PF in breast cancer remains to be clarified. Therefore, in this context, the present study investigated the effects of PF on breast cancer cell proliferat...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2016-03, Vol.78, p.197-203
Hauptverfasser:	Zhang, Qiang, Yuan, Yonghui, Cui, Jianchun, Xiao, Tingting, Jiang, Daqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Line, Tumor Cell Proliferation - drug effects Down-Regulation - drug effects Female Gene Knockdown Techniques Glucosides - pharmacology Humans Internal Medicine Invasion Medical Education Monoterpenes - pharmacology Neoplasm Invasiveness Notch-1 Paeoniflorin Proliferation Receptors, Notch - metabolism Signal Transduction - drug effects
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