Crystalline phase transition of ezetimibe in final product, after packing, promoted by the humidity of excipients: Monitoring and quantification by Raman spectroscopy

[Display omitted] •Pure ezetimibe anhydrous suffered fast solvatomorphic transition.•PLS models allowed the quantification of ezetimibe forms among its excipients.•The quantification models presented RMSEV between 5.6–6.4% for all components.•Most of the anhydrous ezetimibe suffered hydration in the...

Ausführliche Beschreibung