An Examination of Horace Wells' Life as a Manifestation of Major Depressive and Seasonal Affective Disorders
Abstract Horace Wells was a Hartford, Connecticut, dentist whose practice flourished because of his clinical skills. He had an imaginative mind that propelled him to the forefront in several aspects of dentistry. Unfortunately, he suffered a recurrent “illness” that began in the winter and resolved...
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| Veröffentlicht in: | Journal of anesthesia history 2016-01, Vol.2 (1), p.22-27 |
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| container_title | Journal of anesthesia history |
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| creator | Martin, Ramon F., MD, PhD Desai, Sukumar P., MD |
| description | Abstract Horace Wells was a Hartford, Connecticut, dentist whose practice flourished because of his clinical skills. He had an imaginative mind that propelled him to the forefront in several aspects of dentistry. Unfortunately, he suffered a recurrent “illness” that began in the winter and resolved in the spring. These symptoms were compatible with both major depressive disorder and seasonal affective disorder as a qualifier. Wells' introduction of nitrous oxide as an anesthetic was also associated with self-inhalation. This led to periods of hypomania, followed by depression. With the progression to ether, then chloroform, there was an episode of mania in January 1848, followed by depression and suicide. |
| doi_str_mv | 10.1016/j.janh.2015.09.005 |
| format | Article |
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He had an imaginative mind that propelled him to the forefront in several aspects of dentistry. Unfortunately, he suffered a recurrent “illness” that began in the winter and resolved in the spring. These symptoms were compatible with both major depressive disorder and seasonal affective disorder as a qualifier. Wells' introduction of nitrous oxide as an anesthetic was also associated with self-inhalation. This led to periods of hypomania, followed by depression. With the progression to ether, then chloroform, there was an episode of mania in January 1848, followed by depression and suicide.</description><identifier>ISSN: 2352-4529</identifier><identifier>EISSN: 2352-4537</identifier><identifier>DOI: 10.1016/j.janh.2015.09.005</identifier><identifier>PMID: 26898142</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anesthesia & Perioperative Care ; Anesthetics, Inhalation ; Bipolar Disorder ; Chloroform - administration & dosage ; Chloroform - adverse effects ; Connecticut ; Dentistry ; Depressive Disorder, Major - psychology ; History of medicine and histology ; History, 19th Century ; Humans ; Male ; Mood Disorders - psychology ; Nitrous Oxide - administration & dosage ; Nitrous Oxide - adverse effects ; Seasonal Affective Disorder - psychology ; Wells</subject><ispartof>Journal of anesthesia history, 2016-01, Vol.2 (1), p.22-27</ispartof><rights>Elsevier B.V.</rights><rights>2015 Elsevier B.V.</rights><rights>Copyright © 2015 Elsevier B.V. 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With the progression to ether, then chloroform, there was an episode of mania in January 1848, followed by depression and suicide.</description><subject>Anesthesia & Perioperative Care</subject><subject>Anesthetics, Inhalation</subject><subject>Bipolar Disorder</subject><subject>Chloroform - administration & dosage</subject><subject>Chloroform - adverse effects</subject><subject>Connecticut</subject><subject>Dentistry</subject><subject>Depressive Disorder, Major - psychology</subject><subject>History of medicine and histology</subject><subject>History, 19th Century</subject><subject>Humans</subject><subject>Male</subject><subject>Mood Disorders - psychology</subject><subject>Nitrous Oxide - administration & dosage</subject><subject>Nitrous Oxide - adverse effects</subject><subject>Seasonal Affective Disorder - psychology</subject><subject>Wells</subject><issn>2352-4529</issn><issn>2352-4537</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1rGzEQhkVpaEKaP9BD0a29eKOP1WoFpWCStAk45JCEHoVWGlFt15Ir2SH599Xi1IceetIwPO-geQahD5Q0lNDufGxGE382jFDRENUQIt6gE8YFW7SCy7eHmqljdFbKSEgllWxV_w4ds65XPW3ZCZqWEV89m3WIZhtSxMnj65SNBfwDpql8wqvgAZuCDb41sdZlewBvzZgyvoRNhlLCU8Wiw_dgSopmwkvvwW7n9mUoKTvI5T068mYqcPb6nqLHb1cPF9eL1d33m4vlamE567YL0yvmnWR9z7xynZROqlZIwQZoLa9NR6mRnfTcMjlIJqVQgwVq2x7kYCg_RZ_3czc5_d7VL-t1KLbuYyKkXdG0hjvGqWAVZXvU5lRKBq83OaxNftGU6Fm0HvUsWs-iNVG6iq6hj6_zd8Ma3CHyV2sFvuwBqFs-Bci62ADRggu5StEuhf_P__pP3E4hBmumX_ACZUy7XA3XPXRhmuj7-dTzpang9cqk5X8ABW6izw</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Martin, Ramon F., MD, PhD</creator><creator>Desai, Sukumar P., MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160101</creationdate><title>An Examination of Horace Wells' Life as a Manifestation of Major Depressive and Seasonal Affective Disorders</title><author>Martin, Ramon F., MD, PhD ; Desai, Sukumar P., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-a892fd72882f9d677d7945752be4c382fd11a767f3c27b727759bce1c48e7ba13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Anesthesia & Perioperative Care</topic><topic>Anesthetics, Inhalation</topic><topic>Bipolar Disorder</topic><topic>Chloroform - administration & dosage</topic><topic>Chloroform - adverse effects</topic><topic>Connecticut</topic><topic>Dentistry</topic><topic>Depressive Disorder, Major - psychology</topic><topic>History of medicine and histology</topic><topic>History, 19th Century</topic><topic>Humans</topic><topic>Male</topic><topic>Mood Disorders - psychology</topic><topic>Nitrous Oxide - administration & dosage</topic><topic>Nitrous Oxide - adverse effects</topic><topic>Seasonal Affective Disorder - psychology</topic><topic>Wells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martin, Ramon F., MD, PhD</creatorcontrib><creatorcontrib>Desai, Sukumar P., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of anesthesia history</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martin, Ramon F., MD, PhD</au><au>Desai, Sukumar P., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Examination of Horace Wells' Life as a Manifestation of Major Depressive and Seasonal Affective Disorders</atitle><jtitle>Journal of anesthesia history</jtitle><addtitle>J Anesth Hist</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>2</volume><issue>1</issue><spage>22</spage><epage>27</epage><pages>22-27</pages><issn>2352-4529</issn><eissn>2352-4537</eissn><abstract>Abstract Horace Wells was a Hartford, Connecticut, dentist whose practice flourished because of his clinical skills. 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| ispartof | Journal of anesthesia history, 2016-01, Vol.2 (1), p.22-27 |
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| subjects | Anesthesia & Perioperative Care Anesthetics, Inhalation Bipolar Disorder Chloroform - administration & dosage Chloroform - adverse effects Connecticut Dentistry Depressive Disorder, Major - psychology History of medicine and histology History, 19th Century Humans Male Mood Disorders - psychology Nitrous Oxide - administration & dosage Nitrous Oxide - adverse effects Seasonal Affective Disorder - psychology Wells |
| title | An Examination of Horace Wells' Life as a Manifestation of Major Depressive and Seasonal Affective Disorders |
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