Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model

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Veröffentlicht in:Journal of hepatology 2016-03, Vol.64 (3), p.618-627
Hauptverfasser: Chung, Sook In, Moon, Hyuk, Ju, Hye-Lim, Cho, Kyung Joo, Kim, Do Young, Han, Kwang-Hyub, Eun, Jung Woo, Nam, Suk Woo, Ribback, Silvia, Dombrowski, Frank, Calvisi, Diego F, Ro, Simon Weonsang
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container_title Journal of hepatology
container_volume 64
creator Chung, Sook In
Moon, Hyuk
Ju, Hye-Lim
Cho, Kyung Joo
Kim, Do Young
Han, Kwang-Hyub
Eun, Jung Woo
Nam, Suk Woo
Ribback, Silvia
Dombrowski, Frank
Calvisi, Diego F
Ro, Simon Weonsang
description Graphical abstract
doi_str_mv 10.1016/j.jhep.2015.10.007
format Article
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subjects Animals
Apoptosis
Epithelial-Mesenchymal Transition
Gastroenterology and Hepatology
Hedgehog Proteins - analysis
Hedgehog Proteins - physiology
Hepatic stellate cell
Hepatocellular carcinoma
Hydrodynamic transfection
Liver Cirrhosis, Experimental - etiology
Liver Cirrhosis, Experimental - pathology
Liver fibrosis
Liver Neoplasms, Experimental - etiology
Liver Neoplasms, Experimental - pathology
Mice
Mice, Inbred C57BL
Mice, Transgenic
Signal Transduction
Sonic Hedgehog
Transforming Growth Factor beta1 - physiology
title Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model
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