Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model
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Veröffentlicht in: | Journal of hepatology 2016-03, Vol.64 (3), p.618-627 |
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container_title | Journal of hepatology |
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creator | Chung, Sook In Moon, Hyuk Ju, Hye-Lim Cho, Kyung Joo Kim, Do Young Han, Kwang-Hyub Eun, Jung Woo Nam, Suk Woo Ribback, Silvia Dombrowski, Frank Calvisi, Diego F Ro, Simon Weonsang |
description | Graphical abstract |
doi_str_mv | 10.1016/j.jhep.2015.10.007 |
format | Article |
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language | eng |
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source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Animals Apoptosis Epithelial-Mesenchymal Transition Gastroenterology and Hepatology Hedgehog Proteins - analysis Hedgehog Proteins - physiology Hepatic stellate cell Hepatocellular carcinoma Hydrodynamic transfection Liver Cirrhosis, Experimental - etiology Liver Cirrhosis, Experimental - pathology Liver fibrosis Liver Neoplasms, Experimental - etiology Liver Neoplasms, Experimental - pathology Mice Mice, Inbred C57BL Mice, Transgenic Signal Transduction Sonic Hedgehog Transforming Growth Factor beta1 - physiology |
title | Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model |
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