Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model

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Veröffentlicht in:	Journal of hepatology 2016-03, Vol.64 (3), p.618-627
Hauptverfasser:	Chung, Sook In, Moon, Hyuk, Ju, Hye-Lim, Cho, Kyung Joo, Kim, Do Young, Han, Kwang-Hyub, Eun, Jung Woo, Nam, Suk Woo, Ribback, Silvia, Dombrowski, Frank, Calvisi, Diego F, Ro, Simon Weonsang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Epithelial-Mesenchymal Transition Gastroenterology and Hepatology Hedgehog Proteins - analysis Hedgehog Proteins - physiology Hepatic stellate cell Hepatocellular carcinoma Hydrodynamic transfection Liver Cirrhosis, Experimental - etiology Liver Cirrhosis, Experimental - pathology Liver fibrosis Liver Neoplasms, Experimental - etiology Liver Neoplasms, Experimental - pathology Mice Mice, Inbred C57BL Mice, Transgenic Signal Transduction Sonic Hedgehog Transforming Growth Factor beta1 - physiology
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