Maternal microchimerism in health and disease

Circulating maternal cells transfer to the fetus during pregnancy, where they may integrate with the fetal immune and organ systems, creating a state of maternal microchimerism (MMc). MMc can persist throughout the child's life, and it has been implicated in the triggering or perpetuation of ch...

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Veröffentlicht in:	Best practice & research. Clinical obstetrics & gynaecology 2016-02, Vol.31, p.121-130
1. Verfasser:	Stevens, Anne M., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	alloimmunity Animals Autoimmune Diseases - embryology Autoimmune Diseases - genetics Autoimmune Diseases - immunology autoimmunity Chimerism - embryology Female Graft vs Host Disease - immunology HLA Antigens - immunology Humans Immune Tolerance - immunology Inflammation Interleukin-10 - immunology maternal Maternal-Fetal Exchange - immunology microchimerism Obstetrics and Gynecology Pregnancy Programmed Cell Death 1 Receptor - immunology T-Lymphocytes - immunology T-Lymphocytes, Regulatory - immunology Transforming Growth Factor beta - immunology
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