Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication

Background & Aims Yearly, approximately 20 million people become infected with the hepatitis E virus (HEV) resulting in over 3 million cases of acute hepatitis. Although HEV-mediated hepatitis is usually self-limiting, severe cases of fulminant hepatitis as well as chronic infections have been r...

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Veröffentlicht in:	Journal of hepatology 2016-03, Vol.64 (3), p.565-573
Hauptverfasser:	Helsen, Nicky, Debing, Yannick, Paeshuyse, Jan, Dallmeier, Kai, Boon, Ruben, Coll, Mar, Sancho-Bru, Pau, Claes, Christel, Neyts, Johan, Verfaillie, Catherine M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture model Gastroenterology and Hepatology Hep G2 Cells Hepatitis E virus Hepatitis E virus - physiology Hepatocytes Hepatocytes - virology Humans Pluripotent stem cells Pluripotent Stem Cells - cytology RNA, Viral - analysis Virus Internalization Virus Replication
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