Sarglaperoxides A and B, Sesquiterpene–Normonoterpene Conjugates with a Peroxide Bridge from the Seeds of Sarcandra glabra
Sarglaperoxides A (1) and B (2), a pair of unusual sesquiterpene–normonoterpene conjugates with a peroxide bridge, were isolated from the seeds of Sarcandra glabra. The structures and absolute configurations of 1 and 2 were determined on the basis of spectroscopic data analysis, including MS, NMR, C...
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| Veröffentlicht in: | Organic letters 2016-02, Vol.18 (4), p.832-835 |
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| container_title | Organic letters |
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| creator | Wang, Peng Li, Rui-Jun Liu, Rui-Huan Jian, Kai-Li Yang, Ming-Hua Yang, Lei Kong, Ling-Yi Luo, Jun |
| description | Sarglaperoxides A (1) and B (2), a pair of unusual sesquiterpene–normonoterpene conjugates with a peroxide bridge, were isolated from the seeds of Sarcandra glabra. The structures and absolute configurations of 1 and 2 were determined on the basis of spectroscopic data analysis, including MS, NMR, CD, and XRD. The two compounds were screened in antimicrobial, anti-inflammatory, and cytotoxic bioassays and showed moderate bioactivities. |
| doi_str_mv | 10.1021/acs.orglett.6b00112 |
| format | Article |
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Lett</addtitle><date>2016-02-19</date><risdate>2016</risdate><volume>18</volume><issue>4</issue><spage>832</spage><epage>835</epage><pages>832-835</pages><issn>1523-7060</issn><eissn>1523-7052</eissn><abstract>Sarglaperoxides A (1) and B (2), a pair of unusual sesquiterpene–normonoterpene conjugates with a peroxide bridge, were isolated from the seeds of Sarcandra glabra. The structures and absolute configurations of 1 and 2 were determined on the basis of spectroscopic data analysis, including MS, NMR, CD, and XRD. The two compounds were screened in antimicrobial, anti-inflammatory, and cytotoxic bioassays and showed moderate bioactivities.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>26824697</pmid><doi>10.1021/acs.orglett.6b00112</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1523-7060 |
| ispartof | Organic letters, 2016-02, Vol.18 (4), p.832-835 |
| issn | 1523-7060 1523-7052 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1767078217 |
| source | MEDLINE; American Chemical Society Journals |
| subjects | Crystallography, X-Ray Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - isolation & purification Drugs, Chinese Herbal - pharmacology Magnoliopsida - chemistry Molecular Conformation Molecular Structure Nuclear Magnetic Resonance, Biomolecular Peroxides - chemistry Seeds - chemistry Sesquiterpenes - chemistry Sesquiterpenes - isolation & purification Sesquiterpenes - pharmacology Stereoisomerism |
| title | Sarglaperoxides A and B, Sesquiterpene–Normonoterpene Conjugates with a Peroxide Bridge from the Seeds of Sarcandra glabra |
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