Protective Effects of Hippophae rhamnoides L. Juice on Lead-Induced Neurotoxicity in Mice

We examined the effect of Hippophae rhamnoides L. (HRL) juice on lead-induced memory impairment and neuronal damage in the brains of adult mice. Kunming mice were exposed to lead acetate 10 mg/kg body weight for 20 d. Twenty percent and 40% HRL prevented the lead-induced decrease in step-through lat...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2005, Vol.28(3), pp.490-494
Hauptverfasser:	Xu, Yanji, Li, Guangzhe, Han, Chunji, Sun, Lianping, Zhao, Rongjie, Cui, Santian
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholinesterase Animals Avoidance Learning - drug effects Avoidance Learning - physiology Brain - drug effects Brain - metabolism Female Fruit Hippophae Hippophae rhamnoides L lead Lead Poisoning, Nervous System - metabolism Lead Poisoning, Nervous System - prevention & control Male malondialdehyde memory deficit Mice monoamine oxidase Neuroprotective Agents - isolation & purification Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use neurotransmitter Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Oils - isolation & purification Plant Oils - pharmacology Plant Oils - therapeutic use
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