Interactions between low concentrations of ethanol and nicotine on firing rate of ventral tegmental dopamine neurones

This study investigated interactions between ethanol and nicotine on dopamine-sensitive neurone firing in the ventral tegmental area (VTA), recorded in midbrain slices. No changes in spontaneous activity of the neurones were seen with nicotine at 10, 25, or 100 nM; at 250 nM there was a small signif...

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Veröffentlicht in:	Drug and alcohol dependence 2004-08, Vol.75 (2), p.199-206
Hauptverfasser:	Clark, A, Little, H.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Animals Biological and medical sciences Dopamine Dopamine - physiology Dose-Response Relationship, Drug Drug Interactions Ethanol Ethanol - administration & dosage Ethanol - pharmacokinetics Fundamental and applied biological sciences. Psychology Male Mice Neurons - drug effects Neurons - physiology Nicotine Nicotine - administration & dosage Nicotine - pharmacokinetics Psychoanalysis Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Smoking Synaptic Transmission - drug effects Synaptic Transmission - physiology Ventral tegmental area Ventral Tegmental Area - drug effects Ventral Tegmental Area - physiology
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