Duration of drug action of dopamine D2 agonists in mice with 6-hydroxydopamine-induced lesions

Although 6-hydroxydopamine-induced (6-OHDA-induced) rats are a well-known Parkinson’s disease model, the effects of dopamine D2 agonists in mice with 6-OHDA-induced lesions are not completely understood. We produced mice with 6-OHDA-induced lesions and measured their total locomotion counts followin...

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Veröffentlicht in:	Neuroreport 2015-12, Vol.26 (18), p.1126-1132
Hauptverfasser:	Tsuchioka, Akihiro, Oana, Fumiki, Suzuki, Takayuki, Yamauchi, Yuji, Ijiro, Tomoyuki, Kaidoh, Kouichi, Hiratochi, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiparkinson Agents - pharmacokinetics Apomorphine - pharmacokinetics Azepines - pharmacokinetics Benzothiazoles - pharmacokinetics Corpus Striatum - drug effects Corpus Striatum - pathology Disease Models, Animal Dopamine Agonists - pharmacokinetics Ergolines - pharmacokinetics Indoles - pharmacokinetics Injections, Intraventricular Male Mice Motor Activity - drug effects Oxidopamine - pharmacology Parkinsonian Disorders - chemically induced Parkinsonian Disorders - pathology Parkinsonian Disorders - psychology Quinolines - pharmacokinetics Receptors, Dopamine D2 - agonists Tetrahydronaphthalenes - pharmacokinetics Thiophenes - pharmacokinetics
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