Neurobehavioral changes in response to alterations in gene expression profiles in the brains of mice exposed to low and high levels of mercury vapor during postnatal development

This study examined the relationship between neurobehavioral changes and alterations in gene expression profiles in the brains of mice exposed to different levels of Hg0 during postnatal development. Neonatal mice were repeatedly exposed to mercury vapor (Hg0) at a concentration of 0.057 mg/m3 (low...

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Veröffentlicht in:	Journal of toxicological sciences 2014/08/01, Vol.39(4), pp.561-570
Hauptverfasser:	Yoshida, Minoru, Honda, Akiko, Watanabe, Chiho, Satoh, Masahiko, Yasutake, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Avoidance Learning - drug effects Behavior, Animal - drug effects Brain - metabolism Dose-Response Relationship, Drug Down-Regulation - drug effects Female Gene expression Gene Expression - drug effects Learning - drug effects Male Maze Learning - drug effects Mercury Compounds - metabolism Mercury Compounds - toxicity Mercury vapor Mice, Inbred C57BL Microarray Motor Activity - drug effects Neonatal exposure Neurobehavioral effects Spatial Navigation - drug effects Tissue Distribution Up-Regulation - drug effects Volatilization
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