Insulin resistance in obesity can be reliably identified from fasting plasma insulin

Background/Objectives: Insulin resistance is the major contributor to cardiometabolic complications of obesity. We aimed to (1) establish cutoff points for insulin resistance from euglycemic hyperinsulinemic clamps (EHCs), (2) identify insulin-resistant obese subjects and (3) predict insulin resista...

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Veröffentlicht in:	International Journal of Obesity 2015-12, Vol.39 (12), p.1703-1709
Hauptverfasser:	ter Horst, K W, Gilijamse, P W, Koopman, K E, de Weijer, B A, Brands, M, Kootte, R S, Romijn, J A, Ackermans, M T, Nieuwdorp, M, Soeters, M R, Serlie, M J
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443/319/1642/2815 631/443/319/1642/393 692/499 692/700/139 Adipose Tissue, White - metabolism Adult Blood Glucose - metabolism Blood plasma Body composition Body Mass Index Body size Cardiovascular disease Cholesterol Clamps Complications and side effects Cutting resistance Diabetes Diagnosis Endocrinology Epidemiology Fasting Fasting - metabolism Glucose Glucose Clamp Technique Health care Health Promotion and Disease Prevention Homeostasis Humans Hypoglycemic Agents - blood Hypoglycemic Agents - therapeutic use Immunoassay Insulin Insulin - blood Insulin - therapeutic use Insulin Resistance Internal Medicine Liver Liver - metabolism Male Measurement methods Medicine Medicine & Public Health Metabolic Diseases Metabolism Middle Aged Muscle, Skeletal - metabolism Netherlands - epidemiology Obesity original-article Plasma Predictive Value of Tests Public Health Reference Values Sensitivity Testing
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