Association of the rs1801133 variant in the MTHFR gene and sporadic Parkinson's disease

The MTHFR gene has been reported as a susceptibility locus for sporadic Parkinson's disease (sPD). The functional variant rs1801133 has been linked to hyperhomocysteinemia and dopaminergic cell death. Among different populations, Mexican-Mestizos (most present-day Mexicans) have the highest fre...

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Veröffentlicht in:	Folia neuropathologica 2015, Vol.53 (1), p.24-28
Hauptverfasser:	García, S, Coral-Vázquez, Rm, Gallegos-Arreola, M P, Montes-Almanza, L A, Canto, P, García-Martínez, F A, Chavira-Hernández, G, Palma-Flores, C, Dávila-Maldonado, L, Cuevas-García, C F, López Hernández, L B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Case-Control Studies Female Genetic Association Studies - methods Genetic Variation - genetics Humans Male Methylenetetrahydrofolate Reductase (NADPH2) - genetics Mexico - epidemiology Middle Aged Parkinson Disease - diagnosis Parkinson Disease - epidemiology Parkinson Disease - genetics Polymorphism, Single Nucleotide - genetics
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