Evolution of Diffusion-Weighted Magnetic Resonance Imaging Signal Abnormality in Sporadic Creutzfeldt-Jakob Disease, With Histopathological Correlation

IMPORTANCE: Prion diseases represent the archetype of brain diseases caused by protein misfolding, with the most common subtype being sporadic Creutzfeldt-Jakob disease (sCJD), a rapidly progressive dementia. Diffusion-weighted imaging (DWI) has emerged as the most sensitive magnetic resonance imagi...

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Veröffentlicht in:	JAMA neurology 2016-01, Vol.73 (1), p.1-9
Hauptverfasser:	Eisenmenger, Laura, Porter, Marie-Claire, Carswell, Christopher J, Thompson, Andrew, Mead, Simon, Rudge, Peter, Collinge, John, Brandner, Sebastian, Jäger, Hans R, Hyare, Harpreet
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Creutzfeldt-Jakob Syndrome - diagnosis Creutzfeldt-Jakob Syndrome - metabolism Creutzfeldt-Jakob Syndrome - pathology Diffusion Magnetic Resonance Imaging - methods Diffusion Magnetic Resonance Imaging - trends Female Follow-Up Studies Humans Male Middle Aged
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