Activity-dependent regulation of calcium and ribosomes in the chick cochlear nucleus
Highlights • [Ca2+ ]i and ribosomes (Y10B-ir) show rapid changes in NM following deafferentation. • There is a dissociation between how [Ca2+ ]i and ribosomes are regulated. • Selective mGluR receptor blockade during stimulation dissociates the two events. • Blockade of group I mGluRs affects change...
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| Veröffentlicht in: | Neuroscience 2016-03, Vol.316, p.201-208 |
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| creator | Call, C.L Hyson, R.L |
| description | Highlights • [Ca2+ ]i and ribosomes (Y10B-ir) show rapid changes in NM following deafferentation. • There is a dissociation between how [Ca2+ ]i and ribosomes are regulated. • Selective mGluR receptor blockade during stimulation dissociates the two events. • Blockade of group I mGluRs affects changes in both [Ca2+ ]i and ribosomes. • Blockade of group II mGluRs affects only ribosomal changes. |
| doi_str_mv | 10.1016/j.neuroscience.2015.12.042 |
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Hyson, R.L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-22cd0ab85543bb6e55b23e1f179018f18b4bde20380120a43e4af7809e30353f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Amino Acids - pharmacology</topic><topic>Analysis of Variance</topic><topic>Animals</topic><topic>auditory system</topic><topic>Calcium - metabolism</topic><topic>cell death</topic><topic>Chick Embryo</topic><topic>Cochlear Nucleus - drug effects</topic><topic>Cochlear Nucleus - metabolism</topic><topic>deafness</topic><topic>Electric Stimulation</topic><topic>Evoked Potentials, Auditory - physiology</topic><topic>Excitatory Amino Acid Antagonists - pharmacology</topic><topic>Gene Expression Regulation - drug effects</topic><topic>Gene Expression Regulation - physiology</topic><topic>In Vitro Techniques</topic><topic>Indans - pharmacology</topic><topic>metabotropic glutamate receptors</topic><topic>Neurology</topic><topic>Optical Imaging</topic><topic>Ribosomes - metabolism</topic><topic>Time Factors</topic><topic>Xanthenes - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Call, C.L</creatorcontrib><creatorcontrib>Hyson, R.L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Call, C.L</au><au>Hyson, R.L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Activity-dependent regulation of calcium and ribosomes in the chick cochlear nucleus</atitle><jtitle>Neuroscience</jtitle><addtitle>Neuroscience</addtitle><date>2016-03-01</date><risdate>2016</risdate><volume>316</volume><spage>201</spage><epage>208</epage><pages>201-208</pages><issn>0306-4522</issn><eissn>1873-7544</eissn><abstract>Highlights • [Ca2+ ]i and ribosomes (Y10B-ir) show rapid changes in NM following deafferentation. • There is a dissociation between how [Ca2+ ]i and ribosomes are regulated. • Selective mGluR receptor blockade during stimulation dissociates the two events. • Blockade of group I mGluRs affects changes in both [Ca2+ ]i and ribosomes. • Blockade of group II mGluRs affects only ribosomal changes.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>26739326</pmid><doi>10.1016/j.neuroscience.2015.12.042</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-2254-4298</orcidid></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Amino Acids - pharmacology Analysis of Variance Animals auditory system Calcium - metabolism cell death Chick Embryo Cochlear Nucleus - drug effects Cochlear Nucleus - metabolism deafness Electric Stimulation Evoked Potentials, Auditory - physiology Excitatory Amino Acid Antagonists - pharmacology Gene Expression Regulation - drug effects Gene Expression Regulation - physiology In Vitro Techniques Indans - pharmacology metabotropic glutamate receptors Neurology Optical Imaging Ribosomes - metabolism Time Factors Xanthenes - pharmacology |
| title | Activity-dependent regulation of calcium and ribosomes in the chick cochlear nucleus |
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