Chondrogenic potential of human dermal fibroblasts in a contractile, soft, self-assembling, peptide hydrogel

The present paper describes a simple approach to obtain three‐dimensional (3D) cartilage constructs using human normal dermal fibroblasts (hNDFs) cultured in a self‐assembling peptide nanofibre scaffold. During the first days of culture, the 3D constructs underwent morphological changes consisting o...

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Veröffentlicht in:	Journal of tissue engineering and regenerative medicine 2016-02, Vol.10 (2), p.E54-E62
Hauptverfasser:	Bussmann, Bianca M., Reiche, Sven, Marí-Buyé, Núria, Castells-Sala, Cristina, Meisel, Hans Jörg, Semino, Carlos E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ascorbic Acid - pharmacology Biomarkers - metabolism Calcification, Physiologic - drug effects Cell Differentiation - drug effects Cells, Cultured chondrogenesis Chondrogenesis - drug effects Collagen Type II - metabolism dermal fibroblasts Dermis - cytology Fibroblasts - cytology Fibroblasts - drug effects Glycosaminoglycans - metabolism Humans Hydrogel, Polyethylene Glycol Dimethacrylate - pharmacology in vitro Peptides - pharmacology Regenerative medicine self-assembling peptide three-dimensional Tissue engineering Transforming Growth Factor beta3 - pharmacology
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