Pediatric occult methanol intoxication with hyperammonemia
Methanol is metabolized by alcohol and aldehyde dehydrogenases to formic acid, which leads to metabolic acidosis, retinopathy, and damage to optic nerves and basal ganglia. Ammonia accumulation can occur with normal hepatocellular function through over production with gram negative urease-producing...
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| Veröffentlicht in: | The American journal of emergency medicine 2016-02, Vol.34 (2), p.343.e5-343.e6 |
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| container_end_page | 343.e6 |
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| container_issue | 2 |
| container_start_page | 343.e5 |
| container_title | The American journal of emergency medicine |
| container_volume | 34 |
| creator | Cao, Dazhe, MD Maddux, Aline B., MD Mashburn, Danielle, PA-C Vohwinkel, Christine, MD, PhD Wang, George S., MD |
| description | Methanol is metabolized by alcohol and aldehyde dehydrogenases to formic acid, which leads to metabolic acidosis, retinopathy, and damage to optic nerves and basal ganglia. Ammonia accumulation can occur with normal hepatocellular function through over production with gram negative urease-producing organism-induced sepsis, multiple myeloma, some chemotherapeutics, post-bone marrow transplantation, ureterosigmoidostomy, and states of increased catabolism [8,9]. |
| doi_str_mv | 10.1016/j.ajem.2015.06.031 |
| format | Article |
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Ammonia accumulation can occur with normal hepatocellular function through over production with gram negative urease-producing organism-induced sepsis, multiple myeloma, some chemotherapeutics, post-bone marrow transplantation, ureterosigmoidostomy, and states of increased catabolism [8,9].</description><subject>Adolescent</subject><subject>Alcohol</subject><subject>Ammonia</subject><subject>Bone marrow</subject><subject>Diagnosis, Differential</subject><subject>Diagnostic Imaging</subject><subject>Edema</subject><subject>Emergency</subject><subject>Emergency medical care</subject><subject>Enzymes</subject><subject>Ethanol</subject><subject>Extracorporeal Membrane Oxygenation</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Glasgow Coma Scale</subject><subject>Humans</subject><subject>Hyperammonemia - diagnosis</subject><subject>Hyperammonemia - etiology</subject><subject>Hyperammonemia - therapy</subject><subject>Metabolic disorders</subject><subject>Methanol</subject><subject>Methanol - poisoning</subject><subject>Multiple myeloma</subject><subject>Pediatrics</subject><subject>Renal Replacement Therapy</subject><subject>Suicide</subject><subject>Toxicology</subject><issn>0735-6757</issn><issn>1532-8171</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kU2L1TAUhoMozp3RP-BCLrhx03pOepM0IgMyjB8woKCuQ5qeclPb5pq06v33pt5RYRYuQjbP-ybnOYw9QSgRUL7oS9vTWHJAUYIsocJ7bIOi4kWNCu-zDahKFFIJdcbOU-oBEHdi95CdcYkyn3rDXn6k1ts5ercNzi3DvB1p3tspDFs_zeGnd3b2Ydr-8PN-uz8eKNpxDBON3j5iDzo7JHp8e1-wL2-uP1-9K24-vH1_9fqmcELpuahBKeTQSGcbqPO7QrfEReewctxV2tWkldTY7jpeIbdNo5pux4VrudNW8uqCPT_1HmL4tlCazeiTo2GwE4UlGVRSINQaVvTZHbQPS5zy735TQnOudab4iXIxpBSpM4foRxuPBsGsZk1vVrNmNWtAmmw2h57eVi_NSO3fyB-VGXh1Aii7-O4pmuQ8TS77jeRm0wb___7LO3E3-CnrH77SkdK_OUziBsyndbfralEACKh59QtHNZ1x</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Cao, Dazhe, MD</creator><creator>Maddux, Aline B., MD</creator><creator>Mashburn, Danielle, PA-C</creator><creator>Vohwinkel, Christine, MD, PhD</creator><creator>Wang, George S., MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8959-157X</orcidid></search><sort><creationdate>20160201</creationdate><title>Pediatric occult methanol intoxication with hyperammonemia</title><author>Cao, Dazhe, MD ; Maddux, Aline B., MD ; Mashburn, Danielle, PA-C ; Vohwinkel, Christine, MD, PhD ; Wang, George S., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c579t-8077120b6cab0816259de25fc13c2c39c8e97691d4f2312abb7bf425cd2c9a623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Alcohol</topic><topic>Ammonia</topic><topic>Bone marrow</topic><topic>Diagnosis, Differential</topic><topic>Diagnostic Imaging</topic><topic>Edema</topic><topic>Emergency</topic><topic>Emergency medical care</topic><topic>Enzymes</topic><topic>Ethanol</topic><topic>Extracorporeal Membrane Oxygenation</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Glasgow Coma Scale</topic><topic>Humans</topic><topic>Hyperammonemia - diagnosis</topic><topic>Hyperammonemia - etiology</topic><topic>Hyperammonemia - therapy</topic><topic>Metabolic disorders</topic><topic>Methanol</topic><topic>Methanol - poisoning</topic><topic>Multiple myeloma</topic><topic>Pediatrics</topic><topic>Renal Replacement Therapy</topic><topic>Suicide</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cao, Dazhe, MD</creatorcontrib><creatorcontrib>Maddux, Aline B., MD</creatorcontrib><creatorcontrib>Mashburn, Danielle, PA-C</creatorcontrib><creatorcontrib>Vohwinkel, Christine, MD, PhD</creatorcontrib><creatorcontrib>Wang, George S., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cao, Dazhe, MD</au><au>Maddux, Aline B., MD</au><au>Mashburn, Danielle, PA-C</au><au>Vohwinkel, Christine, MD, PhD</au><au>Wang, George S., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pediatric occult methanol intoxication with hyperammonemia</atitle><jtitle>The American journal of emergency medicine</jtitle><addtitle>Am J Emerg Med</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>34</volume><issue>2</issue><spage>343.e5</spage><epage>343.e6</epage><pages>343.e5-343.e6</pages><issn>0735-6757</issn><eissn>1532-8171</eissn><abstract>Methanol is metabolized by alcohol and aldehyde dehydrogenases to formic acid, which leads to metabolic acidosis, retinopathy, and damage to optic nerves and basal ganglia. Ammonia accumulation can occur with normal hepatocellular function through over production with gram negative urease-producing organism-induced sepsis, multiple myeloma, some chemotherapeutics, post-bone marrow transplantation, ureterosigmoidostomy, and states of increased catabolism [8,9].</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26162618</pmid><doi>10.1016/j.ajem.2015.06.031</doi><orcidid>https://orcid.org/0000-0001-8959-157X</orcidid></addata></record> |
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| identifier | ISSN: 0735-6757 |
| ispartof | The American journal of emergency medicine, 2016-02, Vol.34 (2), p.343.e5-343.e6 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; ProQuest Central UK/Ireland |
| subjects | Adolescent Alcohol Ammonia Bone marrow Diagnosis, Differential Diagnostic Imaging Edema Emergency Emergency medical care Enzymes Ethanol Extracorporeal Membrane Oxygenation Fatal Outcome Female Glasgow Coma Scale Humans Hyperammonemia - diagnosis Hyperammonemia - etiology Hyperammonemia - therapy Metabolic disorders Methanol Methanol - poisoning Multiple myeloma Pediatrics Renal Replacement Therapy Suicide Toxicology |
| title | Pediatric occult methanol intoxication with hyperammonemia |
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