MicroRNA-124-3p inhibits the growth and metastasis of nasopharyngeal carcinoma cells by targeting STAT3

The present study investigated the effects of microRNA-124-3p (miR-124-3p) expression on nasopharyngeal carcinoma (NPC) cells and its relevant mechanism. A total of 90 NPC tissues and 85 postnasal catarrh tissues were collected. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to...

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Veröffentlicht in:	Oncology reports 2016-03, Vol.35 (3), p.1385-1394
Hauptverfasser:	XU, SHAN, ZHAO, NING, HUI, LIAN, SONG, MIN, MIAO, ZI-WEI, JIANG, XUE-JUN
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Animals Apoptosis Apoptosis - genetics Cancer therapies Carcinoma Cell cycle Cell growth Cell Line, Tumor Cell Proliferation - genetics Chemotherapy Cyclin D2 - biosynthesis Cyclin D2 - genetics Deoxyribonucleic acid Development and progression DNA Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Health aspects Humans Infections invasion Kinases Matrix Metalloproteinase 2 - biosynthesis Matrix Metalloproteinase 2 - genetics Medical research Metastasis Mice MicroRNA microRNA-124-3p MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism migration Nasopharyngeal cancer Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - pathology Neoplasm Metastasis Otolaryngology proliferation Prostate cancer Radiation therapy Rodents STAT3 Transcription Factor - biosynthesis STAT3 Transcription Factor - genetics Throat cancer Transcription factors Tumors
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