Evaluating Biomaterial- and Microfluidic-Based 3D Tumor Models

Cancer is a major cause of morbidity and mortality worldwide, with a disease burden estimated to increase over the coming decades. Disease heterogeneity and limited information on cancer biology and disease mechanisms are aspects that 2D cell cultures fail to address. Here, we review the current ‘st...

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Veröffentlicht in:Trends in biotechnology (Regular ed.) 2015-11, Vol.33 (11), p.667-678
Hauptverfasser: Carvalho, Mariana R, Lima, Daniela, Reis, Rui L, Correlo, Vitor M, Oliveira, Joaquim M
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Sprache:eng
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