Implantation of recombinant human bone morphogenetic proteins with biomaterial carriers: A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model

This study was carried out to determine the effect of recombinant human bone morphogenetic protein (rhBMP) pharmacokinetics (PK) on rhBMP-induced osteoinductive activity. It was our working hypothesis that the PK of a rhBMP significantly affects its osteoinductive activity. The PK of various rhBMPs...

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Veröffentlicht in:	Journal of biomedical materials research 2000-05, Vol.50 (2), p.227-238
Hauptverfasser:	Uludag, H, D'Augusta, D, Golden, J, Li, J, Timony, G, Riedel, R, Wozney, J M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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