Serum soluble urokinase-type plasminogen activator receptor levels in male patients with acute exacerbation of schizophrenia
Abstract Inflammatory abnormalities have been shown in the pathogenesis of schizophrenia. Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that is measurable in the circulating blood and reflects the inflammation in the body. We aimed to investigate serum suPAR levels in pa...
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Veröffentlicht in: | Psychiatry research 2016-02, Vol.236, p.179-181 |
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container_title | Psychiatry research |
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creator | Genc, Abdullah Kalelioglu, Tevfik Karamustafalioglu, Nesrin Tasdemir, Akif Genc, Esra Sena Akkus, Mustafa Emul, Murat |
description | Abstract Inflammatory abnormalities have been shown in the pathogenesis of schizophrenia. Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that is measurable in the circulating blood and reflects the inflammation in the body. We aimed to investigate serum suPAR levels in patients with schizophrenia who were in acute state and to compare with healthy controls. Forty five patients and 43 healthy controls were included in the study. We found no significant difference in suPAR levels between patients and controls, suggesting that suPAR as an inflammatory marker does not have a role in the inflammatory process of acute schizophrenia. |
doi_str_mv | 10.1016/j.psychres.2016.01.018 |
format | Article |
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Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that is measurable in the circulating blood and reflects the inflammation in the body. We aimed to investigate serum suPAR levels in patients with schizophrenia who were in acute state and to compare with healthy controls. Forty five patients and 43 healthy controls were included in the study. 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Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that is measurable in the circulating blood and reflects the inflammation in the body. We aimed to investigate serum suPAR levels in patients with schizophrenia who were in acute state and to compare with healthy controls. Forty five patients and 43 healthy controls were included in the study. We found no significant difference in suPAR levels between patients and controls, suggesting that suPAR as an inflammatory marker does not have a role in the inflammatory process of acute schizophrenia.</description><subject>Adult</subject><subject>Biomarkers - blood</subject><subject>Case-Control Studies</subject><subject>Disease Progression</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Inflammation - blood</subject><subject>Male</subject><subject>Psychiatry</subject><subject>Receptors, Urokinase Plasminogen Activator - blood</subject><subject>Schizophrenia</subject><subject>Schizophrenia - blood</subject><subject>Schizophrenia - pathology</subject><subject>Soluble urokinase-type plasminogen activator receptor</subject><issn>0165-1781</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2PFCEQhonRuOPoX9hw9NKzQH_QXIxmo67JJh5Wz4Rhqh1maWiBHh3jj7c6s-vBi0klUFS9VcVThFxytuGMd1eHzZRPdp8gbwT6G8bR-idkxXspKslF_ZSsMNBWXPb8grzI-cAYE1yp5-RCdFI2vFcr8vsO0jzSHP289UDnFO9dMBmqcpqATt7k0YX4DQI1trijKTHRBBam5eLhCD5TF-hoUDyZ4iCUTH-4ssf8uQCFn8ZC2mIkBhoHmu3e_YoTDh6ceUmeDcZnePVwrsnXD--_XN9Ut58_frp-d1vZRtSlAtXutjivQrfpZTNwBgofDH6mlbBTrW2UAFk3bd0bNrCa8aGTTNStkrI19Zq8PtedUvw-Qy56dNmC9yZAnLPmsmt43SvUr0l3TrUp5pxg0FNyo0knzZleyOuDfiSvF_KacbQehZcPPebtCLu_skfUmPD2nIDI4Ogg6WwRl4WdQ6BF76L7f483_5Sw3gVnjb-HE-RDnFNAjprrLDTTd8v-l_XzFomwTtR_AG-4r1w</recordid><startdate>20160228</startdate><enddate>20160228</enddate><creator>Genc, Abdullah</creator><creator>Kalelioglu, Tevfik</creator><creator>Karamustafalioglu, Nesrin</creator><creator>Tasdemir, Akif</creator><creator>Genc, Esra Sena</creator><creator>Akkus, Mustafa</creator><creator>Emul, Murat</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160228</creationdate><title>Serum soluble urokinase-type plasminogen activator receptor levels in male patients with acute exacerbation of schizophrenia</title><author>Genc, Abdullah ; Kalelioglu, Tevfik ; Karamustafalioglu, Nesrin ; Tasdemir, Akif ; Genc, Esra Sena ; Akkus, Mustafa ; Emul, Murat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-e95db7419c424874f10e9b74a19957ed95c492e734538a0f0301f6702359775a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Biomarkers - blood</topic><topic>Case-Control Studies</topic><topic>Disease Progression</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Inflammation - blood</topic><topic>Male</topic><topic>Psychiatry</topic><topic>Receptors, Urokinase Plasminogen Activator - blood</topic><topic>Schizophrenia</topic><topic>Schizophrenia - blood</topic><topic>Schizophrenia - pathology</topic><topic>Soluble urokinase-type plasminogen activator receptor</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Genc, Abdullah</creatorcontrib><creatorcontrib>Kalelioglu, Tevfik</creatorcontrib><creatorcontrib>Karamustafalioglu, Nesrin</creatorcontrib><creatorcontrib>Tasdemir, Akif</creatorcontrib><creatorcontrib>Genc, Esra Sena</creatorcontrib><creatorcontrib>Akkus, Mustafa</creatorcontrib><creatorcontrib>Emul, Murat</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Genc, Abdullah</au><au>Kalelioglu, Tevfik</au><au>Karamustafalioglu, Nesrin</au><au>Tasdemir, Akif</au><au>Genc, Esra Sena</au><au>Akkus, Mustafa</au><au>Emul, Murat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum soluble urokinase-type plasminogen activator receptor levels in male patients with acute exacerbation of schizophrenia</atitle><jtitle>Psychiatry research</jtitle><addtitle>Psychiatry Res</addtitle><date>2016-02-28</date><risdate>2016</risdate><volume>236</volume><spage>179</spage><epage>181</epage><pages>179-181</pages><issn>0165-1781</issn><eissn>1872-7123</eissn><abstract>Abstract Inflammatory abnormalities have been shown in the pathogenesis of schizophrenia. 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subjects | Adult Biomarkers - blood Case-Control Studies Disease Progression Humans Inflammation Inflammation - blood Male Psychiatry Receptors, Urokinase Plasminogen Activator - blood Schizophrenia Schizophrenia - blood Schizophrenia - pathology Soluble urokinase-type plasminogen activator receptor |
title | Serum soluble urokinase-type plasminogen activator receptor levels in male patients with acute exacerbation of schizophrenia |
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