Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci

Bitter taste perception in humans is mediated by receptors encoded by 25 genes that together comprise the TAS2R (or T2R) gene family. The ability to identify the ligand(s) for each of these receptors is dependent on understanding allelic variation in TAS2R genes, which may have a significant effect...

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Veröffentlicht in:	Human mutation 2005-09, Vol.26 (3), p.199-204
Hauptverfasser:	Kim, Unkyung, Wooding, Stephen, Ricci, Dante, Jorde, Lynn B., Drayna, Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles bitter taste Chromosomes cSNP Genes Genetic testing Genetic Variation Genomes Haplotypes Haplotypes - genetics Humans Ligands Mutation natural selection Polymorphism, Single Nucleotide Proteins Receptors, Cell Surface - genetics Receptors, G-Protein-Coupled Selection, Genetic Sequence Analysis, DNA TAS2R Taste Taste Buds - physiology
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