Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs

Ag-specific T cell recognition is mediated through direct interaction of clonotypic TCRs with complexes formed between Ag-presenting molecules and their bound ligands. Although characterized in substantial detail for class I and class II MHC encoded molecules, the molecular interactions responsible...

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Veröffentlicht in:	The Journal of immunology (1950) 2000-10, Vol.165 (8), p.4494-4504
Hauptverfasser:	Melián, A, Watts, G F, Shamshiev, A, De Libero, G, Clatworthy, A, Vincent, M, Brenner, M B, Behar, S, Niazi, K, Modlin, R L, Almo, S, Ostrov, D, Nathenson, S G, Porcelli, S A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Blocking - pharmacology Antibodies, Monoclonal - pharmacology Antigen Presentation - genetics Antigens, CD1 - blood Antigens, CD1 - genetics Antigens, CD1 - immunology Antigens, CD1 - metabolism CD1b antigen Cell Line Clone Cells Glycolipids - immunology Glycolipids - metabolism Humans Macromolecular Substances Major Histocompatibility Complex - genetics Major Histocompatibility Complex - immunology Models, Immunological Mutagenesis, Site-Directed Receptors, Antigen, T-Cell, alpha-beta - metabolism T-Lymphocytes - immunology T-Lymphocytes - metabolism
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