Characterization of Two 5-Aminoimidazole-4-carboxamide Ribonucleotide Transformylase/Inosine Monophosphate Cyclohydrolase Isozymes from Saccharomyces cerevisiae

The Saccharomyces cerevisiae ADE16and ADE17 genes encode 5-aminoimidazole-4-carboxamide ribonucleotide transformylase isozymes that catalyze the penultimate step of the de novo purine biosynthesis pathway. Disruption of these two chromosomal genes results in adenine auxotrophy, whereas expression of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2000-07, Vol.275 (27), p.20920-20927
Hauptverfasser:	Tibbetts, Anne S., Appling, Dean R.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-aminoimidazole-4-carboxamide ribonucleotide transformylase ADE16 gene Ade16 protein ADE17 gene Ade17 protein Adenine - pharmacology Cell Fractionation Cross-Linking Reagents - metabolism Dimerization Dimethyl Suberimidate - metabolism Ethanol - metabolism Fluorescent Antibody Technique Fungal Proteins - metabolism Gene Expression Regulation - drug effects Glucose - metabolism Hydroxymethyl and Formyl Transferases - genetics Hydroxymethyl and Formyl Transferases - metabolism Isoenzymes - genetics Isoenzymes - metabolism Kinetics Multienzyme Complexes - genetics Multienzyme Complexes - metabolism Mutation Nucleotide Deaminases - genetics Nucleotide Deaminases - metabolism Purines - biosynthesis Saccharomyces cerevisiae Saccharomyces cerevisiae - enzymology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!