Structure of the Uncleaved Ectodomain of the Paramyxovirus (HPIV3) Fusion Protein

Class I viral fusion proteins share common mechanistic and structural features but little sequence similarity. Structural insights into the protein conformational changes associated with membrane fusion are based largely on studies of the influenza virus hemagglutinin in pre- and postfusion conforma...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2005-06, Vol.102 (26), p.9288-9293
Hauptverfasser:	Yin, Hsien-Sheng, Paterson, Reay G., Wen, Xiaolin, Lamb, Robert A., Jardetzky, Theodore S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baculoviridae - metabolism Biological Sciences Cell Line Cloning, Molecular Crystal structure Crystallography, X-Ray Crystals Dimerization DNA, Complementary - metabolism Head Insecta Mechanical properties Membrane Fusion Microbiology Models, Molecular Molecular structure Monomers Mutation Paramyxovirinae - chemistry Protein Conformation Protein Folding Protein Structure, Secondary Protein Structure, Tertiary Proteins Proteins - chemistry Recombinant Fusion Proteins - chemistry Trimers Viral fusion proteins Viral Fusion Proteins - chemistry Viral Fusion Proteins - metabolism Viral morphology Viral Proteins - chemistry Virology Viruses
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