Two imprinted gene mutations : three phenotypes

Genetic modifications of imprinted genes have been generated in the mouse to investigate the regulation of their expression. They show classical imprinted gene inheritances. Here we describe two imprinted gene mutations deriving from mutagenesis experiments. One is expressed only when transmitted th...

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Veröffentlicht in:	Human molecular genetics 2000-09, Vol.9 (15), p.2263-2273
Hauptverfasser:	CATTANACH, Bruce M, PETERS, Josephine, BALL, Simon, RASBERRY, Carol
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Animals Biological and medical sciences chromosome 2 chromosome 7 Chromosome Mapping Classical genetics, quantitative genetics, hybrids Crosses, Genetic Edema - genetics Female Fetal Growth Retardation - genetics Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Genomic Imprinting Gnas gene Gnasx1 gene Head - abnormalities Igf2 gene Male Mice Mice, Inbred C3H Mice, Knockout Mutation Nesp gene Nespas gene Pedigree Phenotype Receptor, IGF Type 2 - genetics Vertebrata
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