Ethanol Enhances Nicotine's Effects on DRL Performance in Rats

The present experiment examined effects of nicotine (0.0, 0.3, 0.56, and 1.0 mg/kg; IP) and ethanol (0.0, 0.5, 1.5, and 3.0 g/kg; IG) on operant behavior using a differential reinforcement of low response rate (DRL) schedule in rats. DRL schedules are sensitive to effects of nicotine and provide an...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2000-08, Vol.66 (4), p.819-826
Hauptverfasser:	Popke, E.Jon, Fogle, Charles M, Paule, Merle G
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Animals Biological and medical sciences Central Nervous System Depressants - pharmacology Conditioning, Operant - drug effects Dose-Response Relationship, Drug DRL Ethanol Ethanol - pharmacology Male Medical sciences Nicotine Nicotine - pharmacology Nicotinic Agonists - pharmacology Operant behavior Rats Rats, Sprague-Dawley Reaction Time - drug effects Reinforcement Schedule Tobacco, tobacco smoking Toxicology
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