Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal

The neurobiology of nicotine addiction is reviewed within the context of neurobiological and behavioral theories postulated for other drugs of abuse. The roles of various neurotransmitter systems, including acetylcholine, dopamine, serotonin, glutamate, gamma-aminobutyric acid, and opioid peptides i...

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Veröffentlicht in:	Nicotine & tobacco research 2000-02, Vol.2 (1), p.19-37
Hauptverfasser:	Watkins, Shelly S., Koob, George F., Markou, Athina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Humans Medical sciences Mental Disorders - complications Mental Disorders - physiopathology Models, Neurological Neuropeptides - metabolism Neurotransmitter Agents - metabolism Reinforcement (Psychology) Review Article Substance Withdrawal Syndrome - physiopathology Tobacco Use Disorder - complications Tobacco Use Disorder - physiopathology Tobacco, tobacco smoking Toxicology
Online-Zugang:	Volltext
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