Cardioprotective effects of baicalein on heart failure via modulation of Ca(2+) handling proteins in vivo and in vitro

Baicalein is a widely used Chinese herbal medicine extracted from Labiatae plants Scutellaria baicalensis Georgi's dry root, which has multiple pharmacological activities. However, the precise mechanism of baicalein against myocardial remodeling remains poorly understood. The aim of our study w...

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Veröffentlicht in:	Life sciences (1973) 2016-01, Vol.145, p.213-223
Hauptverfasser:	Zhao, Fali, Fu, Lu, Yang, Wei, Dong, Yuhui, Yang, Jing, Sun, Shoubin, Hou, Yuling
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Cardiotonic Agents - chemistry Cardiotonic Agents - therapeutic use Cell Line Fibrosis Flavanones - chemistry Flavanones - therapeutic use Heart - drug effects Heart - physiopathology Heart Failure - drug therapy Heart Failure - metabolism Heart Failure - pathology Heart Failure - physiopathology Male Myocardium - metabolism Myocardium - pathology Rats Rats, Sprague-Dawley Scutellaria baicalensis - chemistry
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