Periprosthetic joint infection
Summary Periprosthetic joint infections are a devastating complication after arthroplasty and are associated with substantial patient morbidity. More than 25% of revisions are attributed to these infections, which are expected to increase. The increased prevalence of obesity, diabetes, and other com...
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| Veröffentlicht in: | The Lancet (British edition) 2016-01, Vol.387 (10016), p.386-394 |
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| creator | Kapadia, Bhaveen H, MD Berg, Richard A, MD Daley, Jacqueline A, BSc Fritz, Jan, MD Bhave, Anil, PT Mont, Michael A, Director |
| description | Summary Periprosthetic joint infections are a devastating complication after arthroplasty and are associated with substantial patient morbidity. More than 25% of revisions are attributed to these infections, which are expected to increase. The increased prevalence of obesity, diabetes, and other comorbidities are some of the reasons for this increase. Recognition of the challenge of surgical site infections in general, and periprosthetic joint infections particularly, has prompted implementation of enhanced prevention measures preoperatively (glycaemic control, skin decontamination, decolonisation, etc), intraoperatively (ultraclean operative environment, blood conservation, etc), and postoperatively (refined anticoagulation, improved wound dressings, etc). Additionally, indications for surgical management have been refined. In this Review, we assess risk factors, preventive measures, diagnoses, clinical features, and treatment options for prosthetic joint infection. An international consensus meeting about such infections identified the best practices and further research needs. Orthopaedics could benefit from enhanced preventive, diagnostic, and treatment methods. |
| doi_str_mv | 10.1016/S0140-6736(14)61798-0 |
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More than 25% of revisions are attributed to these infections, which are expected to increase. The increased prevalence of obesity, diabetes, and other comorbidities are some of the reasons for this increase. Recognition of the challenge of surgical site infections in general, and periprosthetic joint infections particularly, has prompted implementation of enhanced prevention measures preoperatively (glycaemic control, skin decontamination, decolonisation, etc), intraoperatively (ultraclean operative environment, blood conservation, etc), and postoperatively (refined anticoagulation, improved wound dressings, etc). Additionally, indications for surgical management have been refined. In this Review, we assess risk factors, preventive measures, diagnoses, clinical features, and treatment options for prosthetic joint infection. An international consensus meeting about such infections identified the best practices and further research needs. Orthopaedics could benefit from enhanced preventive, diagnostic, and treatment methods.</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(14)61798-0</identifier><identifier>PMID: 26135702</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Alcohol ; Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Anticoagulants ; Arthroplasty, Replacement - adverse effects ; Bacteria ; Biofilms ; Debridement ; Decontamination ; Diabetes ; Drug resistance ; Epidemiology ; Humans ; Infection Control ; Internal Medicine ; Joint Prosthesis - adverse effects ; Joint surgery ; Knee ; Mortality ; Obesity ; Organisms ; Patients ; Perioperative Care ; Prostheses ; Prosthesis-Related Infections - diagnosis ; Prosthesis-Related Infections - economics ; Prosthesis-Related Infections - epidemiology ; Prosthesis-Related Infections - therapy ; Reoperation ; Researchers ; Risk assessment ; Risk Factors ; Royalties ; Staphylococcus infections ; Streptococcus infections ; Substance abuse treatment ; Surgery ; Therapeutic Irrigation ; Transplants & implants</subject><ispartof>The Lancet (British edition), 2016-01, Vol.387 (10016), p.386-394</ispartof><rights>Elsevier Ltd</rights><rights>2016 Elsevier Ltd</rights><rights>Copyright © 2016 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Jan 23, 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c570t-3f97134900ea4e74e0e1cfa75d07137176f6059869841199356823b78d435e6c3</citedby><cites>FETCH-LOGICAL-c570t-3f97134900ea4e74e0e1cfa75d07137176f6059869841199356823b78d435e6c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1880040980?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,64361,64363,64365,65309,72215</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26135702$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kapadia, Bhaveen H, MD</creatorcontrib><creatorcontrib>Berg, Richard A, MD</creatorcontrib><creatorcontrib>Daley, Jacqueline A, BSc</creatorcontrib><creatorcontrib>Fritz, Jan, MD</creatorcontrib><creatorcontrib>Bhave, Anil, PT</creatorcontrib><creatorcontrib>Mont, Michael A, Director</creatorcontrib><title>Periprosthetic joint infection</title><title>The Lancet (British edition)</title><addtitle>Lancet</addtitle><description>Summary Periprosthetic joint infections are a devastating complication after arthroplasty and are associated with substantial patient morbidity. More than 25% of revisions are attributed to these infections, which are expected to increase. The increased prevalence of obesity, diabetes, and other comorbidities are some of the reasons for this increase. Recognition of the challenge of surgical site infections in general, and periprosthetic joint infections particularly, has prompted implementation of enhanced prevention measures preoperatively (glycaemic control, skin decontamination, decolonisation, etc), intraoperatively (ultraclean operative environment, blood conservation, etc), and postoperatively (refined anticoagulation, improved wound dressings, etc). Additionally, indications for surgical management have been refined. In this Review, we assess risk factors, preventive measures, diagnoses, clinical features, and treatment options for prosthetic joint infection. An international consensus meeting about such infections identified the best practices and further research needs. Orthopaedics could benefit from enhanced preventive, diagnostic, and treatment methods.</description><subject>Alcohol</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Anticoagulants</subject><subject>Arthroplasty, Replacement - adverse effects</subject><subject>Bacteria</subject><subject>Biofilms</subject><subject>Debridement</subject><subject>Decontamination</subject><subject>Diabetes</subject><subject>Drug resistance</subject><subject>Epidemiology</subject><subject>Humans</subject><subject>Infection Control</subject><subject>Internal Medicine</subject><subject>Joint Prosthesis - adverse effects</subject><subject>Joint surgery</subject><subject>Knee</subject><subject>Mortality</subject><subject>Obesity</subject><subject>Organisms</subject><subject>Patients</subject><subject>Perioperative Care</subject><subject>Prostheses</subject><subject>Prosthesis-Related Infections - diagnosis</subject><subject>Prosthesis-Related Infections - economics</subject><subject>Prosthesis-Related Infections - epidemiology</subject><subject>Prosthesis-Related Infections - therapy</subject><subject>Reoperation</subject><subject>Researchers</subject><subject>Risk assessment</subject><subject>Risk Factors</subject><subject>Royalties</subject><subject>Staphylococcus infections</subject><subject>Streptococcus infections</subject><subject>Substance abuse treatment</subject><subject>Surgery</subject><subject>Therapeutic Irrigation</subject><subject>Transplants & 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edition)</jtitle><addtitle>Lancet</addtitle><date>2016-01-23</date><risdate>2016</risdate><volume>387</volume><issue>10016</issue><spage>386</spage><epage>394</epage><pages>386-394</pages><issn>0140-6736</issn><eissn>1474-547X</eissn><coden>LANCAO</coden><abstract>Summary Periprosthetic joint infections are a devastating complication after arthroplasty and are associated with substantial patient morbidity. More than 25% of revisions are attributed to these infections, which are expected to increase. The increased prevalence of obesity, diabetes, and other comorbidities are some of the reasons for this increase. Recognition of the challenge of surgical site infections in general, and periprosthetic joint infections particularly, has prompted implementation of enhanced prevention measures preoperatively (glycaemic control, skin decontamination, decolonisation, etc), intraoperatively (ultraclean operative environment, blood conservation, etc), and postoperatively (refined anticoagulation, improved wound dressings, etc). Additionally, indications for surgical management have been refined. In this Review, we assess risk factors, preventive measures, diagnoses, clinical features, and treatment options for prosthetic joint infection. An international consensus meeting about such infections identified the best practices and further research needs. Orthopaedics could benefit from enhanced preventive, diagnostic, and treatment methods.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>26135702</pmid><doi>10.1016/S0140-6736(14)61798-0</doi><tpages>9</tpages></addata></record> |
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| subjects | Alcohol Anti-Bacterial Agents - therapeutic use Antibiotics Anticoagulants Arthroplasty, Replacement - adverse effects Bacteria Biofilms Debridement Decontamination Diabetes Drug resistance Epidemiology Humans Infection Control Internal Medicine Joint Prosthesis - adverse effects Joint surgery Knee Mortality Obesity Organisms Patients Perioperative Care Prostheses Prosthesis-Related Infections - diagnosis Prosthesis-Related Infections - economics Prosthesis-Related Infections - epidemiology Prosthesis-Related Infections - therapy Reoperation Researchers Risk assessment Risk Factors Royalties Staphylococcus infections Streptococcus infections Substance abuse treatment Surgery Therapeutic Irrigation Transplants & implants |
| title | Periprosthetic joint infection |
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