The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma

[Display omitted] Mast cells play an important role in allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. The genus Garcinia of the family Guttiferae is well known as a prolific source of polycyclic polyprenylated acylphloroglucinols and bioactive prenylated xanthones, which...

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Veröffentlicht in:	Biochemical pharmacology 2016-01, Vol.100, p.61-72
Hauptverfasser:	Lu, Yue, Cai, Shuangfan, Nie, Jia, Li, Yangyang, Shi, Guochao, Hao, Jimin, Fu, Wenwei, Tan, Hongsheng, Chen, Shilin, Li, Bin, Xu, Hongxi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Allergic Agents - isolation & purification Anti-Allergic Agents - pharmacology Anti-Allergic Agents - therapeutic use Asthma Asthma - drug therapy Asthma - metabolism Cell Survival - drug effects Cell Survival - physiology Dose-Response Relationship, Drug Female Garcinia Mast cell Mast Cells - drug effects Mast Cells - metabolism Mice Mice, Inbred BALB C Nujiangexanthone A Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Extracts - therapeutic use Syk
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