Natural heterogeneity of α2-antiplasmin: functional and clinical consequences

Human α2-antiplasmin (α2AP, also called α2-plasmin inhibitor) is the main physiological inhibitor of the fibrinolytic enzyme plasmin. α2AP inhibits plasmin on the fibrin clot or in the circulation by forming plasmin-antiplasmin complexes. Severely reduced α2AP levels in hereditary α2AP deficiency ma...

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Veröffentlicht in:	Blood 2016-02, Vol.127 (5), p.538-545
Hauptverfasser:	Abdul, Shiraazkhan, Leebeek, Frank W.G., Rijken, Dingeman C., Uitte de Willige, Shirley
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-2-Antiplasmin - chemistry alpha-2-Antiplasmin - genetics alpha-2-Antiplasmin - metabolism Amino Acid Sequence Humans Models, Molecular Molecular Sequence Data Protein Conformation Protein Processing, Post-Translational Sequence Alignment
Online-Zugang:	Volltext
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