Metabolic engineering of Escherichia coli for 1,3-butanediol biosynthesis through the inverted fatty acid β-oxidation cycle

The feasibility of 1,3-butanediol biosynthesis through the inverted cycle of fatty acid β-oxidation in Escherichia coli cells was investigated by the rational metabolic engineering approach. CoA-dependent aldehyde dehydrogenase MhpF and alcohol dehydrogenases FucO and YqhD were used as terminal enzy...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied biochemistry and microbiology 2016, Vol.52 (1), p.15-22
Hauptverfasser:	Gulevich, A. Yu, Skorokhodova, A. Yu, Stasenko, A. A, Shakulov, R. S, Debabov, V. G
Format:	Artikel
Sprache:	eng
Schlagworte:	acetyl-CoA acetyltransferase acyl coenzyme A alcohol dehydrogenase aldehyde dehydrogenase beta oxidation Biochemistry Biomedical and Life Sciences biosynthesis Escherichia coli ethanol fatty acids fermentation gene expression glucose Life Sciences Medical Microbiology metabolic engineering Microbiology operon pyruvate dehydrogenase (lipoamide) regulon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!