Crystal structure of vespid phospholipase A1 reveals insights into the mechanism for cause of membrane dysfunction

Vespid phospholipase A1 (vPLA1) from the black-bellied hornet (Vespa basalis) catalyzes the hydrolysis of emulsified phospholipids and shows potent hemolytic activity that is responsible for its lethal effect. To investigate the mechanism of vPLA1 towards its function such as hemolysis and emulsific...

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Veröffentlicht in:	Insect biochemistry and molecular biology 2016-01, Vol.68, p.79-88
Hauptverfasser:	Hou, Ming-Hon, Chuang, Chien-Ying, Ko, Tzu-Ping, Hu, Nien-Jen, Chou, Chia-Cheng, Shih, Yan-Ping, Ho, Chewn-Lang, Wang, Andrew H.-J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Hornet venom Lipase Membrane dysfunction Phospholipase A1 Phospholipid hydrolysis Vespa basalis X-ray crystallography
Online-Zugang:	Volltext
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