A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults: e0125954

Background Sequential prime-boost or co-administration of HIV vaccine candidates based on an adjuvanted clade B p24, RT, Nef, p17 fusion protein (F4/AS01) plus a non-replicating adenovirus 35 expressing clade A Gag, RT, Int and Nef (Ad35-GRIN) may lead to a unique immune profile, inducing both stron...

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Veröffentlicht in:	PloS one 2015-05, Vol.10 (5)
Hauptverfasser:	Omosa-Manyonyi, Gloria, Mpendo, Juliet, Ruzagira, Eugene, Kilembe, William, Chomba, Elwyn, Roman, Francois, Bourguignon, Patricia, Koutsoukos, Marguerite, Collard, Alix, Voss, Gerald
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenovirus Human immunodeficiency virus Human immunodeficiency virus 1
Online-Zugang:	Volltext
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