Dysphagia in the high-risk infant: potential factors and mechanisms

Neonatal dysphagia, or abnormalities of swallowing, represent a major global problem, and consequences of dysfunctional feeding patterns carry over into infancy and toddler age groups. Growth, development, and independent feeding skills are all delayed among high-risk infants. Such a group comprises...

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Veröffentlicht in:The American journal of clinical nutrition 2016-02, Vol.103 (2), p.622S-628S
1. Verfasser: Jadcherla, Sudarshan
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description Neonatal dysphagia, or abnormalities of swallowing, represent a major global problem, and consequences of dysfunctional feeding patterns carry over into infancy and toddler age groups. Growth, development, and independent feeding skills are all delayed among high-risk infants. Such a group comprises premature birth, low-birth-weight, congenital anomalies, perinatal asphyxia, postsurgical, and sepsis categories. The conflict between pathophysiologic and pragmatic feeding strategies remains a major conundrum and is largely due to a lack of validated diagnostic approaches amid heterogeneity of the patient phenotype. Thus, well-tested feeding management strategies that can be generalizable are lacking. Furthermore, the aerodigestive symptoms and signs, potential risk factors, and contributory etiologies remain nonspecific. This article presents mechanistic evidence related to the pathophysiologic basis of neonatal dysphagia as well as potential opportunities to improve feeding abilities and long-term development.
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subjects Breastfeeding & lactation
Child Development
Combined Modality Therapy - trends
Congresses as Topic
Deglutition Disorders - diagnosis
Deglutition Disorders - epidemiology
Deglutition Disorders - etiology
Deglutition Disorders - therapy
Dysphagia
Enteral Nutrition - trends
Gastrointestinal Tract - growth & development
Gastrointestinal Tract - physiology
Gastrointestinal Tract - physiopathology
Genotype & phenotype
Humans
Infant Nutritional Physiological Phenomena
Infant, Low Birth Weight
Infant, Newborn
Neonatal care
Neurogenesis
Parenteral Nutrition - adverse effects
Parenteral Nutrition - trends
Pathology
Physiology
Practice Guidelines as Topic
Precision Medicine
Premature Birth - diet therapy
Premature Birth - physiopathology
Premature Birth - therapy
Prevalence
Risk Factors
title Dysphagia in the high-risk infant: potential factors and mechanisms
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