Preoperative octreotide therapy and surgery in acromegaly: associations between glucose homeostasis and treatment response

In acromegaly, high GH/IGF-1 levels associate with abnormal glucose metabolism. Somatostatin analogs (SSAs) reduce GH and IGF-1 but inhibit insulin secretion. We studied glucose homeostasis in de novo patients with acromegaly and changes in glucose metabolism after treatment with SSA and surgery. In...

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Veröffentlicht in:	Endocrine 2016-02, Vol.51 (2), p.298-307
Hauptverfasser:	Helseth, R., Carlsen, S. M., Bollerslev, J., Svartberg, J., Øksnes, M., Skeie, S., Fougner, S. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acromegaly - blood Acromegaly - drug therapy Acromegaly - surgery Acromegaly - therapy Adult Blood Glucose - metabolism Combined Modality Therapy Diabetes Endocrinology Female Glucose Tolerance Test Homeostasis Humanities and Social Sciences Humans Insulin-Like Growth Factor I - metabolism Internal Medicine Male Medicine Medicine & Public Health Middle Aged multidisciplinary Octreotide - therapeutic use Original Article Pituitary Neoplasms - surgery Science Treatment Outcome
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