Antimicrobial activity of the synthetic peptide Lys-a1 against oral streptococci

► The MIC values ranged from 3.9 to 125μgmL−1, while the MBC values ranged from 3.9 to 500μgmL−1. ► The peptide Lys-a1 demonstrated the potential to inhibit biofilm formation in all bacterial species tested. ► Streptococcus parasanguinis showed the greatest susceptibility to the peptide, reducing th...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2013-04, Vol.42, p.78-83
Hauptverfasser:	da Silva, Bruno Rocha, de Freitas, Victor Aragão Abreu, Carneiro, Victor Alves, Arruda, Francisco Vassiliepe Sousa, Lorenzón, Esteban Nicolás, de Aguiar, Andréa Silvia Walter, Cilli, Eduardo Maffud, Cavada, Benildo Sousa, Teixeira, Edson Holanda
Format:	Artikel
Sprache:	eng
Schlagworte:	acetic acid Amino Acid Sequence Amphibian Proteins - chemistry Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology anti-infective properties Antiinfectives and antibacterials Antimicrobial peptide antimicrobials Anura atmospheric pressure Bacteria biofilm Biofilms Biofilms - drug effects Biomass carbon dioxide chlorhexidine Colony Count, Microbial culture media Dental caries Derivatives frogs gentian violet gluconates Hypsiboas Microbial Sensitivity Tests Microorganisms minimum inhibitory concentration Molecular Sequence Data Mouth - microbiology Peptides Peptides - chemistry Peptides - pharmacology solubilization Streptococcus Streptococcus - drug effects Streptococcus mutans Streptococcus mutans - drug effects Streptococcus oralis Streptococcus parasanguinis Streptococcus salivarius Streptococcus sanguinis Streptococcus sanguis - drug effects Streptococcus sobrinus Streptococcus sobrinus - drug effects synthetic peptides
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