Endothelial Targeting of Antibody-Decorated Polymeric Filomicelles

The endothelial lining of the lumen of blood vessels is a key therapeutic target for many human diseases. Polymeric filomicelles that self-assemble from polyethylene oxide (PEO)-based diblock copolymers are long and flexible rather than small or rigid, can be loaded with drugs, andmost importantly...

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Veröffentlicht in:	ACS nano 2011-09, Vol.5 (9), p.6991-6999
Hauptverfasser:	Shuvaev, Vladimir V, Ilies, Marc A, Simone, Eric, Zaitsev, Sergei, Kim, Younghoon, Cai, Shenshen, Mahmud, Abdullah, Dziubla, Thomas, Muro, Silvia, Discher, Dennis E, Muzykantov, Vladimir R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies - metabolism Circulation Diseases Drug Delivery Systems Dynamics Endothelial cells Endothelium, Vascular - metabolism Flexibility Humans Micelles Nanoparticles Nanostructure Polymers Structural integrity
Online-Zugang:	Volltext
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