Tumor Accumulation of NIR Fluorescent PEG–PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model

Cancer therapies are often terminated due to serious side effects of the drugs. The cause is the nonspecific distribution of chemotherapeutic agents to both cancerous and normal cells. Therefore, drug carriers which deliver their toxic cargo specific to cancer cells are needed. Size is one key param...

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Veröffentlicht in:ACS nano 2011-11, Vol.5 (11), p.8710-8720
Hauptverfasser: Schädlich, Andreas, Caysa, Henrike, Mueller, Thomas, Tenambergen, Frederike, Rose, Cornelia, Göpferich, Achim, Kuntsche, Judith, Mäder, Karsten
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Sprache:eng
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