In Vivo Architectonic Stability of Fully de Novo Designed Protein-Only Nanoparticles

The fully de novo design of protein building blocks for self-assembling as functional nanoparticles is a challenging task in emerging nanomedicines, which urgently demand novel, versatile, and biologically safe vehicles for imaging, drug delivery, and gene therapy. While the use of viruses and virus...

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Veröffentlicht in:ACS nano 2014-05, Vol.8 (5), p.4166-4176
Hauptverfasser: Céspedes, María Virtudes, Unzueta, Ugutz, Tatkiewicz, Witold, Sánchez-Chardi, Alejandro, Conchillo-Solé, Oscar, Álamo, Patricia, Xu, Zhikun, Casanova, Isolda, Corchero, José Luis, Pesarrodona, Mireia, Cedano, Juan, Daura, Xavier, Ratera, Imma, Veciana, Jaume, Ferrer-Miralles, Neus, Vazquez, Esther, Villaverde, Antonio, Mangues, Ramón
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Sprache:eng
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