A Thermoresponsive Bubble-Generating Liposomal System for Triggering Localized Extracellular Drug Delivery

The therapeutic effectiveness of chemotherapy is optimal only when tumor cells are subjected to a maximum drug exposure. To increase the intratumoral drug concentration and thus the efficacy of chemotherapy, a thermoresponsive bubble-generating liposomal system is proposed for triggering localized e...

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Veröffentlicht in:	ACS nano 2013-01, Vol.7 (1), p.438-446
Hauptverfasser:	Chen, Ko-Jie, Liang, Hsiang-Fa, Chen, Hsin-Lung, Wang, Yucai, Cheng, Po-Yuan, Liu, Hao-Li, Xia, Younan, Sung, Hsing-Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Bicarbonates Bubbles Carbon dioxide Chemotherapy Delayed-Action Preparations - chemistry Diffusion Doxorubicin - chemistry Drug delivery systems Drugs Encapsulation Hot Temperature Lipid Bilayers - chemistry Liposomes - chemistry Microbubbles Monitors Nanostructure
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