Elevated plasma vitamin B12 levels and cancer prognosis: A population-based cohort study
Highlights • Measuring plasma vitamin B12 levels is used to diagnose vitamin B12 deficiency. • Elevated plasma vitamin B12 has been associated with an increased cancer risk. • This large cohort study shows that cancer patients with high B12 have increased mortality. • This association was independen...
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| Veröffentlicht in: | Cancer epidemiology 2016-02, Vol.40, p.158-165 |
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| container_title | Cancer epidemiology |
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| creator | Arendt, Johan Frederik Håkonsen Farkas, Dóra Körmendiné Pedersen, Lars Nexo, Ebba Sørensen, Henrik Toft |
| description | Highlights • Measuring plasma vitamin B12 levels is used to diagnose vitamin B12 deficiency. • Elevated plasma vitamin B12 has been associated with an increased cancer risk. • This large cohort study shows that cancer patients with high B12 have increased mortality. • This association was independent of cancer stage, comorbidity, age and sex. • Further prospective studies are needed to examine the clinical applicability of these results. |
| doi_str_mv | 10.1016/j.canep.2015.12.007 |
| format | Article |
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blood</topic><topic>Calendars</topic><topic>Cancer</topic><topic>Cancer therapies</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cohort Studies</topic><topic>Comorbidity</topic><topic>Confidence intervals</topic><topic>Denmark - epidemiology</topic><topic>Drug dosages</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Health risk assessment</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Internal Medicine</topic><topic>Laboratories</topic><topic>Leukemia</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical prognosis</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Neoplasms - blood</topic><topic>Neoplasms - diagnosis</topic><topic>Neoplasms - epidemiology</topic><topic>Plasma</topic><topic>Population</topic><topic>Prescription drugs</topic><topic>Prognosis</topic><topic>Registration</topic><topic>Registries</topic><topic>Regression analysis</topic><topic>Risk Assessment</topic><topic>Studies</topic><topic>Survival Rate</topic><topic>Tumors</topic><topic>Vitamin B 12</topic><topic>Vitamin B 12 - 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| ispartof | Cancer epidemiology, 2016-02, Vol.40, p.158-165 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Adult Age Aged Aged, 80 and over Biomarkers, Tumor - blood Calendars Cancer Cancer therapies Child Child, Preschool Cohort Studies Comorbidity Confidence intervals Denmark - epidemiology Drug dosages Epidemiology Female Health risk assessment Hematology, Oncology and Palliative Medicine Humans Infant Infant, Newborn Internal Medicine Laboratories Leukemia Male Medical diagnosis Medical prognosis Middle Aged Mortality Neoplasms - blood Neoplasms - diagnosis Neoplasms - epidemiology Plasma Population Prescription drugs Prognosis Registration Registries Regression analysis Risk Assessment Studies Survival Rate Tumors Vitamin B 12 Vitamin B 12 - blood Young Adult |
| title | Elevated plasma vitamin B12 levels and cancer prognosis: A population-based cohort study |
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